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SpeedOfSound
Help! C-C connections are not well treated in most texts. I may use this topic to further define what I am after here because I'm not even sure of that.

First question. I have the Thalamus book. I have the Hippocampus book. Were I to buy the best cortex book what would it be?

I'm looking for the best detail, yet the best hierarchy, of C-C connections available. Online would be great but most of the connectome sites leave me frustrated.

For instance if I want to know all of what V1 connects to. From major highways to the minor. Where would I look?

SpeedOfSound
I'm awake now. Sort of.

First I would like a good resource for the gross anatomy of the white matter involved with the cortex. There are the big fans from the thalamus and BG that are talked about, the EC, and IC. Then there is a badly described swath of C-C bundle that runs antero-posterior across each hemisphere. I have one text book that mentions it and only briefly. They are very vague about which areas are connected to which.

The problem comes up in some of my speculation about consciousness. I think it was Crick and Koch that said that V1 doesn't have enough reciprocal connections with other cortical areas to be a detailed source of visual consciousness then that was contradicted by Edelman.

Very little time is ever spent on C-C details. Frustrating. Anyone have resources for this?
Ginger Campbell MD
QUOTE(SpeedOfSound @ Apr 11, 2010, 02:33 AM) *

Help! C-C connections are not well treated in most texts. I may use this topic to further define what I am after here because I'm not even sure of that.

First question. I have the Thalamus book. I have the Hippocampus book. Were I to buy the best cortex book what would it be?

I'm looking for the best detail, yet the best hierarchy, of C-C connections available. Online would be great but most of the connectome sites leave me frustrated.

For instance if I want to know all of what V1 connects to. From major highways to the minor. Where would I look?


This is probably not exactly what you are looking for, since it doesn't go into the neuroanatomical circuits, but I think you would enjoy Cortex and Mind: Unifying Cognition by Joaquin M. Fuster.
SpeedOfSound
Not exactly what I asked for but definitely what I am interested in. Thank you.

I have asked this question about cortical connections in a number of places. No answers. Either I am smoking the ganj on this one or I have found a nice project for someone to fill a gap.

SpeedOfSound
I will try here and further explain why I want a clear and detailed connectome and what I think clear would consist of.

In a recent article in science daily they found that nouns and verbs lit up different sections of cortex when learned. I would quickly guess that connections to the primary auditory cortex were involved.

The question is why are areas of the cortex carved up to perform certain functions. There are the obvious connections to sensory modalities. But between verbs and nouns one can learn more by finding out what is different between the two.

I would make a wild guess that the verb areas are intersected by motor areas and the noun by the ventral visual stream. But what else?

Knowing what else will tell us about the function and suggest possible subfunctions that can be tested. I'm looking for intersections.

The clear part is where it gets tough. The intersections will be by gradation. The boundaries are fuzzy. Still, we may find some way represent these things by hierarchy. The main connections and then the minor. Perhaps there is a way to use weighted digraphs or intermixing colored sets to show the connectome.

I can't even find reliable details on the major long range pathways that crisscross the brain. Like the major antero-posterior path. Where are the entrance and exit ramps?

Someone must be working on this.

SpeedOfSound
Thank you thank you for the book suggestion. Just what the doctor ordered! Now I wait by the door for amazon to deliver.

SpeedOfSound
http://www.ploscompbiol.org/article/info:d...al.pcbi.0010042

The Human Connectome: A Structural Description of the Human Brain

(thanks to GrahamH at rationalia)
benkids


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