I thought about this as like everyone I guess, I always felt better after having a physical activity while not on meds. if it's similar, it's like x10 the effect. I laugh off anything and feel very good. Seems too much to be just a normal chemical release from the body or my brain is really messed up and releases too much chemicals. I didn't think about it but I take the second Stablon pill of the day 1~2h before I go run so maybe it's related.

Thanks for the answers Hey Hey and YoungS

Though most of the time after work-out I get a feeling of wellbeing and a better mood but I also DID experience what you describe a couple of times after work-out, first time it happened I was in such a euphoric mood I almost choked on food while laughing about something that wasn't really that funny (if I think about it), I actually thought this euphoric mood was caused by the whey protein I am taking. I still can't relate it to the Stablon I am taking, I take it at midnight and work-out next day at 5pm.

How often do you experience this euphoric mood?
As from tomorrow I'm going to take Stablon 1 hour prior to work-out to see what happens! I'll let you know..

Adrenalin is just great eh?

Is it Adrenalin? U sure?

Why not? Those effects can be due to it, especially if you really put the effort in.

How do you mean put the effort in, those days I have a adrenalin-kick are just the same days as other days where I don't have it.

It's like a dose-dependent effect, the more exercise the more adrenalin the more euphoria, for example.

I can have higher/better than usual mood on normal day but it cannot compare to after working out. It's pretty much like what somebody not anxious would experience once in a while I think. I don't take proteins, food supplements or any other med than Stablon before working out/running. The only other med I take is the benzo which I only take once a day (1 pill) the evening now.

I'll check to see if you experienced the same thing tomorrow.

Well.. I gave it a try and didn't notice anything good or bad, I guess the dopamine and like Hey Hey says the adrenalin (and other body chemicals) that kick in.

So it's not the med and probably (most likely) means that I have some kind of chemical imbalance.

Thanks for the input guys.

Hello, I am from the U.S but currently live in Norway. I suffer from depression and get all the meds that I would normally get back home here. I really want to try Stablon, but am not sure if it is used here in Norway or not. I dont see my doc for a few weeks and you know how that is when you dont feel good. I have looked it up as much as I could and have no idea if they prescribe Stablon here. I tried searching the web under all the brand names and the generic name and nothing. Searched the pharmacy website here with the same info and nothing. I have a feeling that they dont use it here and I am thinking the best thing to do is to order it online. I just dont want to wait 2 weeks just to find out they dont prescribe it here and than have to order it online and wait another 3 weeks for delivery and that is if it makes it through customs here. The way this place is, I seriously doubt they have it in this Country, but if you know if they do prescribe it in Norway or have any idea where to find a list of countries that do or do not prescribe Stablon, I would really appreciate any information. Of course it is a holiday weekend and nothing is open for me to call and find out for a few days. Thank you guys very much for all your help!

@ normal

You may want to start ordering it online... Norwegian wikipedia says: tianeptin, ikke registrert i Norge (Tianeptine is not registered in Norway)

http://no.wikipedia.org/wiki/Selektiv_sero...reopptakshemmer

Hello, I'm new here. I'm 41 and I live in Paris, France. I'm glad I can discuss here with you.
This is what brings me here : I'm a bpd sufferer and over the 5 last years my depressive tendency has been increasing so much as to become terribly disabling.

I had been on SSRI for 10 years (on and off, more on than off) before I gave some thinking into why my depression wouldn't be alievated, let alone cured.

My MD switched me from Zoloft to seroplex....To no avail...I continued deteriorating (

Eventually, I decided to STOP Seroplex, and after two weeks of withdrawal to switch to Stablon.
The first three weeks of that experimentation were hellish. I thought I'd have to stop working for a while cause I felt far too depressed, disabled, vulnerable and miserable. The first two weeks, I stopped Seroplex without taking Stablon. I took Stablon the third week. I was still feeling very bad although I noticed some temporary improvement in my overall state.

Then I figured out that may be I should try to take more stablon. I went from 3 to 4 ; and then 6.
I feel way better now.

Thanks God, stablon works.
Now I think, I'll be still better off with some ritalin, but here in France it is quite hard to get a prescription

LOL, ironic, u waisted 10 years on SSRI's while Servier (France) invented Stablon :-S
Anyway, glad it also works for u, thanks for sharing.

Mmmm I don't know what to think of your answer


Well, unfortunately I'm not a doctor and until recentely I was not knowledgeable in brain chemistry and AD.
At the beginning -that is ten years ago- Zoloft really had a wonderful effect on me. Alas it did not last.
Finally I'm a bit angry that I had to ask my doctor for Stablon when what I was offered was just to switch to prozac, another SSRI again (just incredible !!!)

Well, you partially confirmed what I tried to say with my comment ;-)

I still don't get your point.

Has anyone shared a similar experience ?
Has any bpd sufferer found a suitable AD treatment ?

I meant, it's ironic that they prescribed you SSRI's (in my opinion pure poison) when they have such a good drug as Stablon (invented in France) all a long.

You're right.
What's infuriating is the lack of knowledge displayed by GP -and even psychiatrists- in the treatment of depression. A month ago, I was prescribed Prozac by a psychiatrist. Of course, by then I knew better...I threw away her prescription. I just couldn't believe it

When all I needed was dopamine all I got offered was serotonine
But why ?

Tell me about it.. If it was up to my psychiatrists knowledge I would still walk around like a (over-medicated) freakin' zombie!

For example, last month I asked him about the new AD (Valdoxan), he didn't know anything about it, he didn't even heard of the name Valdoxan and today... it's here on the market. Last month I had to tell him how it works and the side-effects profile. And he is allowed to call himself the professional, unbelievable, it's the world upside down!

I just want to emphazise how dramatically and how quickly (within a week !) I shifted from a deep depressive state with strong motor inhibition to a much better condition.

Stablon works fine with me.
I'm grateful, it's such a relief !

hi all
first sorry for my english,i'm italian 36 years
from 1 year i'm in thailand and from 1 year begin my first dap and after 2 months i decide to go to psicoterapeut
after 1 mont of rivotril and lexapro(escitalopram) or zoloft he admitted my intollerance to ssri
so i begin take nortriptyline 25 mg and xanax 0,5 morning and 0,5 evening
after 2 monts increase nortriptyline to 35 mg and xanax 0,25 also afternoon
In this years things go bettere thanks also to sport and stop smoking
I,m feel only anxious with a lot of phisical symptoms
2 months ago i move city so i change doctor also,xanax very slow less from 1,25 per day to 0,5 per day and things go god,begin again to smoke not more of 6-7 cigarettes per day and less sport,and anxity increase again with a lot of phisical symptoms
So go to know new doctor,and he say toi do psycotherapy beahoviour comportamental(same i do before in under city)and change medicine,i inform he about my intollerance to ssri,he giv me stablon,say decrease nortriptyline from 0,35 to 0,25 and increase again xanax from 0,5 to 0,75 per day,and take stablon 12,5 x 3 a day
First week i'm feel very stranger,maybe because i less nortriptyline,after 2 week better and the doctor say to decrease again nortriptyline to 10 mg
So now i'm in xanax 0,75 per day(3x0,25)after meal and stablon12,5 x 3 before eat and noritren 10 mg in bedtime
Now really i'm feel also a little depressed,sometimes tired about dizziness,headache,iperventilation and tachicardia,maybe is this the reason of my mild depression(the doctor say a'm only panic disorder and anxious),3 week allready of stablon that maybe doesn't work fully,maybe because i mixed with xanax and noritren,ao maybe because need more time,like a 2 months
The doctor say wait,until we eliminated noritren fully,and begin decrease xanax(almost 10 months allready of xanax)
Sincerely i'm very tired of take a lot of medicine and i desire only to take stablon and nothing more,tired of xanax,i'm feel almost everyday headache,stunned,stone and tired
Any body use stablon toghether xanax?
Thanks a lot

Has anybody here tried getting it in powder form like milkmoth suggested? If so, pm me where you got it and for how much, please!

Better yet, has anybody found it from a country with more reliable manufacturing standards than China? Considering what's been found in their exported food product in the past couple of years, I'm a little leery of China. Can you buy the stuff from pharmaceutical companies in Europe?

I don't see why you couldn't mix it with fillers the same way pill manufacturers do, and then measure it out so you can be sure you're getting the correct dosage. You ought to even be able to press it into tablets yourself.

It would sure as hell be cheaper, and if each of us is only doing this for our own use and not selling the tablets on, I can't see any illegalities involved. Especially since it doesn't appear to have much potential for recreational use.

Hi,

I am new to the forum pretty excited about the stuff I read about Stablon. I currently take Celexa (citalopram) 30 mg a day to treat Anxiety

Would like to switch to Stablon. Anyone out the make the switch from an SSRI to Stablon? If so how did you go about it, did you slowing cut back on the SSRI while taking Stablon?

Was concerd since the SSRI inhibits the sertion while Stablon enhances, seem like the action of one would cancel out the other.

Thanks.

Edited to erase: Found a company selling it and posted about them, then found out they won't take orders from individuals unaffiliated with a corporate entity already in their customer data base.

Bummer.

Quitting cold turkey with SSRI might result in brain-zaps/shocks or other discontinuation side-effects, nothing to worry about, it's only quite annoying.

About brain-shock and SSRI withdrawal side-effects visit links below or page 3 of this thread...

Hi Awakening,

Thanks for the info. I have tried slowly to get off of it, cutting down by 10mg a week. But when I did it felt terrible.

I will check out page 3. Any other advice for taper off SSRI and replacing with Stablon.

Thanks again.

Your welcome,
The name is YoungS btw, awakening is my posts contribution promotion ;-)

There is not much advise I can give, speaking from my own AD switch experience, you can start with Stablon right after you come off the SSRI (if you were using MAO type AD's it would be a different story and even be "dangerous" to do that).
Just make sure that you don't confuse SSRI withdrawal side-effects (see link) with side-effects of Stablon (because side-effects on Stablon are rare).

good luck!

Where's the best place to order stablon if you live in the US?

Where's the best place to order stablon if you live in the US?

anti-aging systems

They are not cheap. But I never gotten my shipment seized by customs. So they know what they're doing..
If someone else got any alternatives. I'm all ears...

Hey, I previously was Flesh of reality in that thread.

My state has improved since February. I feel better. I can do things now, whereas before I was stuck, hopelessly stuck : I couldn't do a thing, In addition I was blighted with strong emotional pain and a lot of suicidal thoughts. Shortly, I was deeeeeeeeply depressed.

Now I take 6 stablon a day + caffeine (200mg) when required.
I live again. As simple as that.

I just can't believe it.

I would go to ****** (edited). Great service and very reliable. Btw, they are not a pharmacy but rather a go-between that deals directly with overseas pharmacies. They take your money then place the order with a pharmacy. Very safe and products are good quality.

Stablon well may be a smart drug.

First update on Valdoxan in comparising with Stablon:

It's my first week on Valdoxan, and compared to Stablon, it's quite more effective for me, I am in a very stress-full situation right now and Valdoxan calms my thoughts, whereas Stablon made my thoughts more on the horizon. I noticed that I sleep a little more on Valdoxan but did not feel any overall fatigue like I did when Stablon wheres off. I did not notice any (bad) side-effects on Valdoxan or Stablon.

For, who is interested..

This is not a forum on which you should post marketing information. I also recommend that you remove the many links on your site to this forum that imply that BrainMeta recommends your products or has in some way validated them through discussion.

Hi,

I am new to this froum but have been trying Stablon for about 3 weeks now.

I started taking the recommended 12.5mg 3 times a day dose and for the first few weeks it did seem to help me in that my mood seemed better and my depression seemed to have lifted. Generally I did feel better although this could be related to placebo effect.

The main problem I have with it is that I have troubled concentrating, focusing and thinking clearly during the day whilst trying to get work done. Strange as I thought it was supposed to help with these things.

I would like to percivere with Stablon as there are very few side effects especially sexual and fatigue related which are prevalent when on SSRi's such as Seroxat which I have taken before.

My doctor has suggested adding Ritalin and I myself also thought of maybe adding Piracetam or Modafinil after reading various posts on this site.

It may also be that upping the Stablon dosage would help?

Has anyone else experienced similar concentration problems whilst on STablon?

Any advice would be most welcome.

Thanks

Second update on Valdoxan in comparising with Stablon:

It's been a couple of months on Valdoxan, it's effect on my mood is noticeable within 1 hour after taking it, it has very subtle mood alleviating properties without the "euphoria" that comes with Stablon. It also has good (sadly, not great) anxiolytic effects like Stablon. At the beginning it improved my sleep, now it's effect on a good night sleep is gone, I wake up 2 times at night, that's a big minus (I do start my day refreshed, a little +). On Stablon I had very vivid dreams (I don't like to dream) and woke up 1 time at night, (in this case it's a +).
(Because of it's effect on my mood I had taken Valdoxan for a couple days, 1x25mg at 12pm and 1x25mg at 6pm. It improved my mood great but made me drowsy because of it's effect on the melatonin (I guess). I have to discuss it with my pdoc if it f&%$s up my melatonin receptors (I'll report back on this).)

I am wondering if someone has tried the combo Valdoxan & Stablon or can give me advise on it's safety? I searched the web on this but couldn't find anything about this combo. Don't wanna be the first guinea pig ;-)

I started taking Stablon just over a week ago and I felt a big improvement after just the second dose. I have PTSD and have suffered from hypervigilance since my teenage years. After the second dose my hypervigilant feelings were cut by 80%. I'd say Stablon is a pretty good AD, but even better for anxiety. I too have been stuck for years and SSRI's worked some, but never really took away my anxiety like Stablon does. I'm taking 3 x 12.5 right now, but thinking of upping dosage to 4 a day. It's encouraging that 6 works well for you, since I seem to have been as bad as you at times.

For those who are looking for a place to order Stablon (tianeptine) the best price by far is from pharmacyescrow.com. I pay about $.70 a pill and ordering from the European pharmacy usually only takes just over a week for delivery to USA. Another tip is to order the generic version because you'll actually get the real stuff. I ordered generic tianeptine and what came was Stablon in Stablon packaging, but I paid the generic price. Also, pharmacyescrow is very safe and I have never been ripped off. They have really good customer service too and will keep you informed about your order every step of the way. It's just too bad that Stablon is not in the U.S., since I have full medical insurance and would love to pay only about $10 a month for my supply.

Another thing about Stablon vs. SSRI's. There is a lot of argument about the different efficacy of each drug, but I think their efficacy is downstream and the reuptake inhibiting or enhancing of serotonin is of less importance. These meds seem to stimulate neurogenesis, which affects brain plasticity, more than anything else. For my money, though, Stablon is better at this. Go to tianeptine.com for more information on this argument.

Also, servier.com (the French manufacturer) has a good video on their site about Stablon and it's affects on brain plasticity.

Hi

What did you mean by "made my thoughts more on the horizon"?

I will by trying Stablon and Valdoxan combo in a couple of weeks when it arrives, so would be interested in any updates

Thanks

My thoughts and feelings are more intense on Stablon, not like an SSRI that numbs you.
I don't have much to add as an update.
- Valdoxan tempered my mood-swings (I like Valdoxan the most because of this)
- Increased libido (on Stablon also, but the 'soldier production' on Stablon was less)
- My doc. recommended to keep taking it before going to bed.
- My sleep has returned to 1 time awakening.
- Anxiety is still an issue on either drug.

I recommend these sites for other experiences with Valdoxan:
Agomelatine Psychonauts Google Groups
http://groups.google.com/group/agomelatine...chonauts/topics

- It's safe to use Valdoxan and Stablon together:
http://www.imminst.org/forum/topic/37189-v...tine-melatonin/
http://www.imminst.org/forum/forum/6-supplements/ for other threads about Valdoxan

Hi everyone, I thought that I’d add my own experiences to this great thread as it’s such a useful resource for new people, it helped me hugely so I thought I’d give a little back…

I’ve been down the usual SSRI path and nothing has ever worked for me before I discovered Stablon. It’s as if someone opened the blinds and I feel alive for the first time in years, if not ever. The thing that I love most (apart from the obvious benefits) is that it is such a clean drug, apart from a very slightly dry mouth I get no side effects at all, zero

I have been using this now for a few months and I have experimented widely with dosage as I know that the standard 12.5mg is very low and in initial trials doses of up to 300mg a day were tried. I started with the recommended dose of 3 x 12.5mg which gives very little effect, and gradually increased to find the point at which I ceased to gain any benefit, and that point for me is 150mg a day which I take as 3 x 50mg doses, which is 4 tablets, 3 times a day (normally 10am, 4pm and 10pm). At this level I still have no side effects and I have also had liver and kidney functions tests and they are all normal too

There are a few points that I’d like to make, I’d love input on any or all of these…

Firstly, does anyone know if there is a generic Stablon out there in 50mg tablets (or anything larger than 12.5) as this is costing me a fortune…

Secondly I was fascinated by a post from Milkmoth, unfortunately he seems to have only ever made one post but he said…


I love his ingenuity, but I can see a potential flaw in his thinking and I’d like some input from anyone who understands the chemistry of all this to give some input. Although Tianeptine is the active ingredient in Stablon, it is not the ONLY ingredient and if you look on the product sheet you will find that the tablet also contains mannitol. Now I have zero medical experience, all I know is what I have researched, but according to Wikipedia, “Mannitol is used to open the blood-brain barrier by temporarily shrinking the tightly coupled endothelial cells that make up the barrier. This makes mannitol indispensable for delivering various drugs directly to the brain (e.g., in the treatment of Alzheimer's disease)”. So it would seem that although you can purchase Tianeptine, if you just take it neat then it will not be able to get into your brain therefore it effectively will not work, does that sound logical?

And thirdly I would love to know what dosage people have found works best for them. Although everyone reacts differently and has a different ‘sweet spot’ I think that it would be a great addition to this thread if people could see at a glance who takes what and what the most effective level seems to be. It would be great if a poll could be added to the thread giving options from the standard daily dose of 37.5mg up to 150mg that I take, or even higher, what does everyone think? But either way it would be great if people just posted in this thread what dosage they are using?

Thanks everyone, take care and be happy

In the context here, mannitol is probably a simple filler used to give a tablet some bulk and make it handleable and/or chewable. It also offers some sweetness when required. Another common filler is lactose.

Hi, yes I considered that but as the ingredients include other things like corn starch I assumed that they were the fillers. It just seemed strange that as mannitol is specifically used to get drugs past the blood brain barrier, which is where the Tianeptine needs to be to work, surely it's inclusion in Stablon must be to achieve that rather than to just act as a filler?

Corn starch is used as a disintegrant or a binder. This physical formulation discussion could go on for a long time. Take it from me that the mannitol will be a filler. It's use as a further active ingredient would be unlikely (aside from an anecdotal implication) for a barrowful of reasons. I'm no expert on the particular product in question but to be able to titrate dosages of two active ingredients with pharmacological usefulness would be difficult. If the use of mannitol in the way you describe was an intended property of the formulation then that should be indicated on the packaging and the manufacturer should be able to substantiate their claims. (This is not to dispute the property of mannitol as influencing the permeability of the BBB through hyperosmolarity effects, just its usage for such a purpose in said formulation).

Thanks for the reply, it makes sense, I'm just trying to understand as much as I can about it and what the options are

The other thing that ws interesting about Milkmoth's post was the effect that he seemed to get from a very small amount of raw Tianeptine, 'a speck' he said I think, any idea why the neat product would appear to be so much more potent tham a 12.5mg Stablon tablet?

Did anyone get smarter as a result of taking Stablon?

I don't think it makes you smarter as in better or faster at understanding things. It does mean you can do a lot more work though such as studying or work work. At the end of the day I notice that if I cant keep my eyes open but have some work to finish off, within half an hour of a stablon makes me not feel sleepy any more. Not speedy...but just not sleepy. If really pushed I'd say that if I had to do some complicated integrative problem solving or be creative, Id do better without the stablon, which focuses thinking but constricts it a bit. On the other hand to churn through volumes of work it helps with mental stamina. Likewise it helps with fast response in discussions but somehow makes it harder to find the right words so makes you a bit less articulate. The effects are subtle so I am not a 100% on these points but thats how it seems. I only have a low dose now. I used to take 6 per day but now only 1 or 2.

BTW Thanks for the links YoungS

I experienced somewhat the same effects.

Is it possible to get it over to the uk over the net? Anyone who has had success?