I am also very interested in Valdoxan, it may soon be available in The Netherlands.
I have links about the outcome of the trials that are done, it looks very promising:


http://www.medicalnewstoday.com/articles/22334.php

http://www.medicalnewstoday.com/articles/85521.php

http://www.medicalnewstoday.com/articles/130389.php

http://www.medicalnewstoday.com/articles/140248.php

Hello, I have just bought Stablon and have great hopes regarding this medicine.
My problem is that I've eaten Aurorix (moclobemide, MAOI-A inhibitor) until three days ago.
I have seen that it's not recommended to start treatment with Stablon until 15 days after finishing treatment with moclobemide.
Since it sucks being without any medication I want to start with Stablon now. So I wonder if anyone has tried to start with Stablon sooner than 15 days or knows what could happen, why it seems to be so important to wait?

best regards!

@ Operatic

Welcome,

Stablon might interact with the Aurorix still in your system (just like a SSRI combined with a MAO), in other words, it is possible u get screwed (sick) if u are not patient.

Good luck with Stablon, share your Stablon experience here, if u want to.

that MAOI loses its activity 100% in 24 hours, youre fine

Try taking your usual dose with a regular full meal and report back to us.
Mind you, you've seem to have been taking this for much longer than I have. I haven't even tried it again due to its price. Also the scarcity in literature regarding the drug is putting me off as well.

strange as i went from one page of this thread to the next, the previous page posts kept popping up instead of the new ones.

but anyway, reading all the comments here, it seems that Stablon has worked for alot of folks for anxiety and depression issues mainly but not so much anyone posting about it enhancing their memory, learning abilities, focus, etc.

with the exception of Tonic, so far not much has been said about that cognitive enhancing from people who dont suffer from any depression or anxiety issues.

Stablon definitely works to remove about a quarter of a person's bad feelings, if 25 to 30 pills per day are taken. for any drug to remove 25% of bad feelings is amazing since every other drug classified as an antidepressant removes 0% of bad feelings.

clinical experience shows that "large" amounts would be safe - except we dont know what affect on the liver it might have for some people. who can afford large amounts? how are you going to get it, keep ordering international packages? no way, forget all that

so in the end its a non-option

Where's the best place to order it from?

I'm not a chronically depressed person but sometimes I have these drastic mood changes and go through short periods of deep depression.

I'm going through a difficult period in my life right now, so I decided to try STABLON: I've been taking it for two days and it seems to be working. I feel happy and relaxed but the mind is a tricky thing and I'm not familiar with antidepressants.

So my question is this: should I take STABLON continuoulsy to start seeing results or is it possible to take it on demand (e.g. before speaking in public or any other stressful activity that may increase my anxiety levels)?

Hi metropolis,

U can use it however your needs are, continuously or on demand.

Over the last half year I have used it from continuously to a few days per week or none at all.
Right now, after a period of 4 clean weeks I am on 2 at midnight for relaxation.

the wikipedia entry on stablon now says it rots your body and causes amputations

the PsyOps disinformation has begun, its going to be attacked like Amineptine.

I tried to order from AuroPharm, but they won't ship to Norway. Any other non fake places online that I can get it from?

This came about because some heroine users in russia "supposedly" injected it instead of taking it orally.
I personally don't believe anything that comes out the russian media. The fact that Putin still remains as popular as when he was president (and still calling the shots) tells me their population is whipped into submission, and eager to believe whatever is shoved down their throats.

Well, I finally received my first order today, and took my first dose. I definitely noticed something half an hour later, and it wasn't bad. I've done my research, and I know it will take several weeks for full effect.

I'll update as to how things go.

(I have had terrible problems with side effects from most other antidepressants and atypicals.)

Day six on Stablon and Deplin (L-methylfolate). Very definite improvement in mood and energy in general, with slight "boosts" after each dose. None of the intolerable side effects I experience with other drugs. I do have slight insomnia, which Stablon literature says is common and temporary.

Very encouraging!

Good that it also works for you, hope it continues!! Keep us updated..

Hi folks,

This is my first contribution to this board. I've been taking Stablon for, um, less than a week, so far I am in love! I've taken ADs on and off for 15 years, starting with Paxil before going through Prozac, Zoloft, Celexa, Wellbutrin, etc. I would say I'm low-to-moderately depresed and have never been hospitalized or taken any other psychoactive drugs except a little recreational psychedelic use back in the 70s. All SSRIs have worked briefly and then made me too sleepy to function well; also I had a bit of unwanted weight gain, so I have never taken any of these drugs religiously. Celexa worked the best as it didn't stimulate my appetite; I always stayed at a low dosage (20-40mg per day).

Through internet research I found out about Provigil/Modiafinil a year ago and started taking that in doses of 100-200 mg per day. This drug has been quite helpful. It provides a needed boost of energy and positiveness to my negative & slothful mindstate. While I started on my AD use with a psychiatrist in the US I now buy drugs through international pharmacies or in Mexico.

I've always reacted to all ADs within hours; I haven't needed the weeks or months that some others do for the efects to kick in. So the first day I took Stablon I noticed a calm and serene glow which is extremely pleasant, I've also had rich dreams. I feel amazingly able to deal with the challenges and streses of my life and am less snappy, more social. My sense of humor is much larger (thank god). Of course I realize that this may be a honeymoon period. I'm taking 2 12.5mg tablets a day now along with 100mg of Modiafinil, and will build up to 3 gradually.

It was great to find this board and I'll keep you informed of how it goes. If anyone else has any specifics about dosages or other re: a modiafinil/tianeptine combo I'd be interested.

erika

Hi erika,

This is from Wikipedia:

Tianeptine is synergistic and has been used in conjunction with other drugs such as modafinil.[3][4]

Helen

Thank you so much!

This was the first time I took an antidepressant, but I'm very happy with the results. I recently went through some personal problems that made me feel depressed, but STABLON made me confident, optimistic, energetic. There were no side effects (e.g. no sexual side effects), just some insomnia and restlessness - which were mild and transient.

I'm not an expert, but I'm convinced that STABLON is effective and safe.

You really shouldnt be getting any effect at all from just 2 12.5 mg pill per day. effects dont even begin to start till about 10 or 15 pills a day. i cannot explain why you get an effect out of just 2, that is very strange.

thanks, Helen.

"Dosage of tianeptine in most clinical trials has ranged from 25mg to 50mg per day. Currently, 3 x 12.5mg = 37.5mg daily is standard. "Patients"/healthcare consumers are rarely encouraged to explore the optimal dosage of their prescribed psychotherapeutic agent by their doctor. This is regrettable because individual optimal dosage regimen can vary a lot. Obviously, there are risks as well as advantages to encouraging self-titration. A post-genomic era of truly personalised medicine is probably decades away. In the meantime, not everyone is temperamentally or educationally well-equipped to perform the incremental dosage increases or decreases over time that are needed to identify what regimen personally works best, especially when there is a pronounced therapeutic time-lag. One consequence is that very few people ever receive their optimal dosage of psychotropic medication - or for that matter "lifestyle drug" of choice. This failure exacerbates the poor response-and-remission rates to antidepressant drugs and other psychoactive pharmaceuticals. The actual therapeutic dosage range of tianeptine probably ranges from less than 12.5mg to as much as 300 mg daily; but these figures depend on "animal models" and the usual horrible experiments." - tianeptine . com

I have been on tianeptine for nine days, (3 x 12.5 mg, once or twice four) and have had noticed VERY significant improvement in my own mood, as I've posted above. As above, I also noted that I realize full benefit doesn't kick in until about week four, but geez ... even if it doesn't get better than this, I know I'll be okay. You can't know the struggle I've had finding an antidepressant or mood stabilizer (or they've even tried <gack> antipsychotics) that don't cause lethal or intolerable side effects. I've been basically housebound with major depression and social anxiety disorder since Thanksgiving. Yesterday I went BY MYSELF to the Colorado State Fair and had an absolute blast, went to the shows, rode the ferris wheel, talked to people, got flirted with, bought rocky mountain oysters (okay, gotta try em once), and then went to the Foreigner concert.

You're talking to someone who's been living on Ensure and protein bars for months, and now I have a kitchen full of fresh food - and a CLEAN HOUSE.

I don't plan to use 10-15 pills a day. I don't want a high. I need an antidepressant, and so far, Stablon is delivering as advertised.

Will Stablon show up on an employment drug test?

No, almost certainly not. Drug tests are drug-specific. When you test for drugs, you actually have to have a separate test for each drug you're testing for, though there are kits that group these panels together (which is what most employers use.) A typical multi-panel test will test for marijuana, opiates like codeine and hydrocodone, barbiturates, cocaine, ecstacy, methadone, amphetamines, PCP, and oxycodone (which is a separate screen from the other opiates). Tianeptine should not show a positive result on any of these screens.

Many people are under the assumption that drug screens test for all drugs, but they don't. They are very sensitive and can only detect the presence of THAT chemical in your body. A ten-year-old boy in Texas died of methadone poisoning two days after having a drug screen in an emergency room, simply because the ER didn't include the methadone panel in his drug screen - there was no index of suspicion for them to believe that a ten-year-old boy would be overdosing on methadone. Hence, his drug screen was negative. The pharmacy that was found to have mistakenly put methadone into his Ritalin bottle went out of business.

What's up ppls,

This is for sure the best thread on the net about stablon.

Now for my questions, has anyone ever ordered off of life-extesion-drugs?
Is it ok for me to take 3 pills a day when I first start?

Thx.

Hi tropicz,

First question I don't understand.
Second question, yes, it is ok to take 3 pills a day when u start.

Tropicz is asking if anybody has bought from the website called Life Extension Drugs. I haven't, but it looks good so I hope it is legitimate.

Yeah, these fotos look pretty fake to me. Actually I only saw 1 foto.

@youngS, Thx now I feel safe.

@erikaf, So far so good my order was shipped last monday n this site has been around from 2003 says Whois website lookup.
I'm not sure but I think these are not generics n they are very affordable vs many other places. The main reason why I picked them was cuz they ship to Canada which most of the others don't, oh n another cool thing is they take paypal.

I will keep u guys updated when I get them with my results.

Hey ppl if I can find amineptine (survector) should get it or is stablon better, or are they both diff?

If I should get it then I would prefer a pm where it's at insted of my days of digging on the net plz lol

Thx.

2 years ago I also wanted to find and see the effects of amineptine on me, didn't find it back then (searched a lot!) and as you may know, as from 2005 it isn't produced anymore and I guess it is taken completely out of the market by now.
If you can find it though, I wouldn't take the risk to use it (if I was u), you never know if it is the real one or just fake, expired, placebo, xtc or whatever!

Why are you using Stablon? as a smart-drug or for depression? I would say, try the new anti-depressant, Valdoxan - Agomelatine (also produced by Servier). It has a very promising profile and trial results! Over a month or so (when it's in the Dutch drug pharmacies) I can share my experience on Valdoxan in comparising with Stablon.
(btw. bad news for ppl in the US, FDA approval of Valdoxan is around 2012.)

Hey YoungS,
Very good point about not trying amineptine cuz it could be fake or expired etc, never thought of that. Sense you asked, I am taking stablon for major depression.
So for this newer drug I heard about it, but read that's it's not available yet and was very interested in it myself. Do you know where it's first available by any chance?

Thx.

Source Valdoxan.com: Valdoxan® received EU marketing authorisation in February 2009 and is now available in several countries worldwide for the treatment of adult patients with MDD.

I think it is all ready on the market in Germany, France and Brittain.
Valdoxan received European Union marketing authorisation in February this year and is now available in Germany, Argentina, Brazil, Russia and Ukraine for the treatment of adults with MDD. And within months in all EU countries.
I'm sorry, I don't have a site for you where you can buy it. But I'll look it up and report back to you.

Found this online pharmacy in Canada:
http://www.canadadrugs.com/prescription/pr...xan+25mg/13012/

Lol ya I just saw that one but they don't have it.

Thx for the help btw.

ok i got my stuff n dont feel shit wtf is going on am i suppose to feel anything or is my shit fake?

plz help me out if my shit is fake or not, it taste sweet n on the back has all these serial codes n bar codes n in french labatories servier n big writing coaxil then tianeptine sodium 12.5 mg, shit sounds pretty real.
what can it be, do i need like alot for it to work?
my first time i took 6 in one day and every other day on, still didnt feel happy n shit!!

plz help me

thx.

Hello.

I wanted to post my experience with Stablon (tianeptine sodium).

I've tried so many neuro drugs to help me for depression to basically just feel good about my life.

Nothing worked... until I got a hold of Stablon. Even the pills are sugar coated! So funny.

Anyway... it works so well for me. The best thing I like about it is you don't get hooked on the stuff. And I can go without for a few days without any side-effects or withdrawls.

I can also go over my daily dosage when I want to just perk up and take a drive out to the country. It's very nice to just feel good for a change without any jitter or strinjent effect.

Ok... So, I live in the USA. It costs me $55 for 60, 12.5mg pills from overseas. I stopped doing that.

I was able to order 80 grams of pure Tianeptine Sodium from a chem company in China. Don't ask, because I'm not telling. Do some googling on it and you'll find it. I just don't want to ruin it for myself and others.

So 80 grams at $300 is about 6500 doses. That means for $50 I'm not getting 60 pills... I am getting 1000!

Warning about using Stablon in pure form. Just a speck does the trick. It comes in a off-white powder that clumps together in small little crumbs. Like I said... just a speck is good.

And remember... be responsible. Great thing is, Stablon has a very low toxicity so it's difficult to overdose, but still please be careful.

One last note... Stablon is not a recreational drug. It's a mood lifter so don't expect like your going to trip like ecstasy or anything. It's appropriately labeled an anti-depressant for a reason. And it helps people like me "get on with it" and have some small joy in my day to day life.

Take care everyone.

Uhm. I thought servier had tianeptine's formula a secret. Do you really feel the same effects as servier's own?

Hi Milkmoth.

Are saying you somehow just take 'a speck', and that you don't take it in pill form?

Isn't that a little loosey goosey, in terms of measuring? How big is a speck??? My idea of a speck is almost certainly much different than yours...

Can you tell me where you got the Stablon pills, as I am in Canada, and it's just impossible here, now.

I did recieve one shipment form PharmacyEscrow, I believe, but nobody will ship here anymore.

Thanks, my friend.

Whipper

Hi, Could you please tell me where you sourced Stablon - I'm in Canada, and the online services won't ship here anymore. I'm near the US border, however, and it would be easy to bring it in to Canada.

Thank you so much,

Whipper

Could you please tell me where you acquired Stablon from??

Thanks so much.


Don - (Whipper)

....

Yeah, this same thing happened to me. Stablon makes me pass out and feel really weak during the day. I have high cortisol levels, but apparently they need to be high for a reason. I've felt good at certain times on stablon, but overall became disfunctional and messed up my sleep cycle. I too wish it had no direct effect on cortisol. As an antidepressant should reduce cortisol indirectly by repressing emotional pain.

i believe there are natural ways to alter cortisol levels but forgot what they are and you can google them

another thing that alters cortisol levels is CYP3A4 status, higher CYP3A4 metabolizes cortisol

people think of CYP3A4 status only in terms of what it does to medical drugs you take, but guess what, it effects endogenous chemicals too and this is overlooked. Cortisol has very high affinity for CYP3A4 which will break it down

when people dont respond to stablon thats really serious because there arent many limbic based drugs to hit limbic depression - if you dont have limbic depression then its not as serious - you could probably respond to something like Trileptal the mood stabilizer whereas people like me cant

Tianeptine is an antidepressant that has proven its value in the treatment of depression, due to its antidepressant efficacy, its ability to alleviate anxiety symptoms of depression without sedation, and its excellent acceptability profile.

Tianeptine (Stablon, Coaxil, Tatinol), is structurally similar to the tricyclic antidepressants. Unlike the tricyclics, however, it enhances the reuptake of serotonin instead of blocking it. Tianeptine has strong antidepressant and anxiolytic properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, making it particular suitable for use in elderly patients and in those following alcohol withdrawal as these patients are known to be more sensitive to the adverse effects of psychotropic drugs.
Currently, tianeptine is approved in a host of countries in Europe, Asia and Latin America.

Tianeptine shows efficacy against serious depressive episodes (major depression), comparable to amitriptyline, imipramine and fluoxetine, but with fewer side effects. It was even more effective than maprotiline in a group of patients with coexisting depression and anxiety. Tianeptine also displays significant anxiolytic properties and is useful in treating a spectrum of anxiety disorders including panic disorder, as evidenced by a study in which those administered 35% CO2 gas on paroxetine (Paxil) or tianeptine (Stablon) therapy showed equivalent panic-blocking effects. A 2005 study in Egypt demonstrated tianeptine to be effective in men with depression and erectile dysfunction. Tianeptine is also being studied in the treatment of ADD/ADHD.

Before taking any prescription medicine, it is important that you consult your doctor!

Has anyone tried combining:

Agomelantine 25 mg per night


and tianeptine 3 x 12.5 mg


i plan on starting this combo very soon and i would assume the synergy should be amazing.

found this post while looking up for Stablon side efects and since some of you have been taking it for a long while, I wonder if anyone noticed this "side" effect.

I suffer from GAD (with Social Anxiety) and tried, and gave up, SSRI/SNRI because I always ended up with more side effects than good effects while on these drugs. I've been put on Stablon (3x12.5mg day) for like a year now and I did have the somewhat "euphoric" effect at the beginning before the effect wears off.
Now, I'm 30 past and thought it was time to start doing some real sport. The thing is whenever I go run I feel high once I'm done. Not drug like high more like an adrenaline rush type high. Not really sure if it's solely because of Stablon as I'm also taking benzo, which I'm slowly getting off, so I thought to ask. I was wondering if anyone had experienced something similar while only taking Stablon. I think it's related to mixing benzos and Stablon as I started taking the benzos a while after after taking Stablon and I don't remember having such "problem" while only taking Stablon. I want to be sure.

It's the first time in my life I take benzos to help with anxiety and it's by far the crappiest drug I've ever taken. Last summer I thought I had a sudden Alzheimer breakdown. Seriously. They literally killed my short-term memory. when I was talking with somebody, I often couldn't even remember what the heck I was the topic of the conversation after a monent or mixed info. For the lighter side-effects I just couldn't remember where I had just left stuff like keys. Very disturbing when you suffer from Anxiety.

Thanks,

Chris

@ bben

I don't think there are people that tried that combination yet. Agomelatine is quite new, it is on the market in just a few countries.

Agomelatine works as an antagonist on the serotonin 5-HT2C receptor whereas Stablon it's 'unknown', here is what wikipedia says about Stablon:

it enhances the extracellular concentration of dopamine in the nucleus accumbens.[2]
Tianeptine, indicated as a thymoleptic, reduces the effects of serotonin in the limbic system and the pre-frontal cortex

With this information given, maybe someone in this thread with more incite can give more info..


Caution with the combo...!

@ neobubu

Doing sport releases dopamine (giving a natural 'high') and maybe it interacts with the effects of Stablon. I don't really know the experience because I take Stablon 6 hours after I'm done with sport.

Doing sports causes the release of so many biochemicals, some through normal physiological mechanisms and some through injury (eg. red cells break during the pounding blood blood receives as it passes through the feet during jogging) that interactions with drugs are extremely complex and poorly understood.