Chips Coming to a Brain Near You
By Lakshmi Sandhana
02:00 AM Oct. 22, 2004 PT
In this era of high-tech memory management, next in line to get that memory upgrade isn't your computer, it's you.

Professor Theodore W. Berger, director of the Center for Neural Engineering at the University of Southern California, is creating a silicon chip implant that mimics the hippocampus, an area of the brain known for creating memories. If successful, the artificial brain prosthesis could replace its biological counterpart, enabling people who suffer from memory disorders to regain the ability to store new memories.

And it's no longer a question of "if" but "when." The six teams involved in the multi-laboratory effort, including USC, the University of Kentucky and Wake Forest University, have been working together on different components of the neural prosthetic for nearly a decade. They will present the results of their efforts at the Society for Neuroscience's annual meeting in San Diego, which begins Saturday.

While they haven't tested the microchip in live rats yet, their research using slices of rat brain indicates the chip functions with 95 percent accuracy. It's a result that's got the scientific community excited. [...]

Berger's team began its research by studying the re-encoding process performed by neurons in slices of rat hippocampi kept alive in nutrients. By stimulating these neurons with randomly generated computer signals and studying the output patterns, the group determined a set of mathematical functions that transformed any given arbitrary input pattern in the same manner that the biological neurons do. And according to the researchers, that's the key to the whole issue. [...]