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LifeMirage
Lee Crost's AntiAging-Cognitive Regimen

Aside from exercise & diet (and until nanotech, gene & stem therapy catch up) I believe various compounds exist today that can make a dramatic impact on our health, such as greatly reducing our risk of disease, helping to slow, maintain if not reverse some aspects of aging, and even going as far as enhancing our own physical & mental abilities. In order to keep up with the latest in bioresearch I take several compounds, which in my opinion is based on reasonable scientific studies. This list changes as new research is done daily and to keep my life more interesting. Also some dosages will vary based on what is needed depending on my day. I started a simpler version of this regimen over 15 years ago and have been blood testing regularly since.

Caution: This is my own personal regimen. I strongly recommend everyone do their own research and consulting their healthcare professional before taking anything listed below. Also this list is not complete I still have much to add.

Last Updated: 07-2008

Pharmaceutical - Nutritional

Daily/Every Other Day or Weekly/Monthly*:

Glycation Breakers:

Alagebrium chloride (ALT-711) 50 mg (w/f)
N-Acetyl-L-Carnosine eye drops 4x each eye
N-Acetyl-L-Carnosine 500 mg (w/f)

Telomere Lengtheners:

Carnosine 500 mg (w/f)
TA-65 25 mg

Glycation Inhibitors:

Benfotiamine 300 mg (w/f)
Pyridoxamine 300 mg

Mitochondria Antioxidants:

Chlorophyllin 400 mg (w/f)
R-Lipoic Acid (from na-rala/rala/rmct/sr) 450 mg
R-Dihydrolipoic acid 150 mg
3-Carboxy-3-Oxopropanoic acid 300 mg

SOD Upregulators

Deprenyl 1 mg (w/f)
Rasagiline 0.5 mg (w/f)
Bacopa 50% 300 mg

GliSODin 100 mg
Wolfberry 20% 100 mg


Mitochondria Upregulators

N-Acetyl-L-Carnitine 1 gram
Acetyl-L-Carnitine Arginate 1 gram
Propionyl-L-Carnitine 1 gram
Idebenone 180 mg (w/f)
Mitoquinone 50 mg (w/f)
Ubiquinol 200 mg (w/f)
Ubiquinone 50 mg [water soluble]
Decylubiquinone 50 mg

Cellular Membrane Agents

PPC (PhosChol, Lipostabil) 900 mg (w/f)
Centrophenoxine 500 mg (w/f)

Nootropics:

Piracetam 2,400 mg
Aniracetam 750 mg (w/f)
Oxiracetam 800 mg
Hydergine 2.25-5 mg (w/f)
Vincamine 10 mg (w/f)
Vinpocetine 10 mg (w/f)
Oxopocetine (vinpocetine citrate) 10 mg
Pyritinol 400-800 mg
CDP-Choline (Citicoline) 500 mg
Alpha GPC 300 mg
Desmopressin (Vasopressin) 2 sprays*

Brain Nutrients:

L-Huperzine A 100 mcg (w/f)
Galantamine 4 mg (w/f)
Cytisine 750 mcg*

Japanese Pharmaceutical Grade Ginkgo Biloba extract 120 mg
L-Theanine 500-1,000 mg
Lithium (as orotate) 20 mg (w/f)
Forskolin 100 mg
Methylcobalamin 30 mg
L-Methylfolate 1.6 mg
P-5-P 100-200 mg
L-Glycine 3-5 grams (w/f)*
Ashwaganda 450 mg

Myo-Inositol 5 Grams*
Scyllo-Inositol 1 gram

Antioxidants:

Trans-Resveratrol 250 mg (w/f)
Melatonin 1 mg (w/f)
Tocotrienols 125 mg (w/f)

Immune:

Biostim 2 Courses a Year
Imm-kine 1 Course a Year
DENTAVAX 1 Course a Year
RESPIVAX 1 Course a Year
UROSTIM 1 Course a Year
Russian Choice Immune 1 Course a Year
Shark Liver Oil 1-2 grams
Lactoferrin 2-3 grams
Monolaurin 1-2 grams

Isoprinosine 1 gram
Thymic Protein A 1 Packet

Dietary Supplements:


Ortho-Core 9 caps [even days] (w/f)
LEF Mix 9 tabs [odd days] (w/f)
Sulfur (as MSM) 1,023 mg (w/f)
TMG citrate 1-2 gram
Whey Protein 20-40 grams
EPA/DHA (from Omega 3's-Fish Oil) 2.6 grams (w/f)
Vitamin K2 15 mg (w/f)
Serrapeptase 6 tablets
Adapton 2 softgels
Polaprezinc (Zinc-Carnosine) 150 mg (w/f)
Strontium (citrate) 227 mg (w/f)
Silicon (Orthosilicic Acid) 6 mg (w/f)
L-Taurine 2 grams
Astaxanthin 4 mg
Cordyceps 1 gram
Creatine 1 gram
D-chiro-Inositol 1 gram
Creatine Ethyl Ester 1 gram

and more soon to be added...

Dental/Topical:

Toothpaste:


Colgate Total: Fluoride Ion (0.14% w/v), Triclosan (0.30%).
Biotene: Lactoperoxidase (100gm), Glucose Oxidase, Lysozyme, Sodium Monofluorophosphate.
LEF Toothpaste: A blend of essential oils and H2O2

I alternate different products for best inhibitory effects.

Mouthwash:

Listerine tartar control: Essential Oil blend, zinc sulfate.
(Well studied for protecting gums and teeth)
Crest Pro-Health 0.07% cetylpyridinium chloride

(Antibacterial)
Peridex: 0.12% chlorhexidine gluconate
(Very long lasting antibacterial effects)
Biotene: Lysozyme (40mg), Lactoferrin (15mg), Glucose Oxidase (2,500 units), Lactoperoxidase (2,500 units)
Hydrogen Peroxide 3%
(Antibacterial and teeth whitener)

Body Wash:

HIBICLENS: 4% chlorhexidine gluconate
(A long lasting safe antibacterial compound)


Nutribiotic: Grapefruit seed extract

Hair:

Dr. Proctor's Hair Shampoo & Serum: 3-carboxylic acid pyridine n-oxide*
Decos*
Nizoral*
(cleans hair sebum, inhibits DHT, and kills fungus that may effect hair growth)

Skin:

Prevage (Idebenone 1%)*
Beta-Alistine (Carnosine)*
Derma Q-Gel (Ubiquinol)*
Aminocare Cream (phenylacetylglutamine, phenylacetylisoglutamine)*
(a glutamine metabolite formula)
Tretinoin (Retin A) 0.05%*
(a vitamin A analog)


Diet


Food is a dual edge sword. While the wrong diet greatly increase your risk of disease and death, the right one can extend your life and improve your overall health. In the last 100 years we have been able to identify the health benefits to certain foods as well the negative impacts of others and the best ways to prepare them.

Foods Prepared:
50-75% raw, steamed, and/or very lightly boiled.
(No microwave, no deep fried, and only rarely oven cooked)

Foods Consumed:
80%-90% Organic- vegetables, grains, fish, nuts, seeds, berries, etc.

Remaining - legumes, organic fermented & raw dairy products, turkey, chicken, and rarely organic grass fed red meat.

Foods Avoided:
GMO crops, pasteurized dairy/juices, hydrogenated oils, irradiated foods, cloned meats and refined flours/sugars.

More details to be added�


Exercise [Physical/Mental Training]


Sleep

Too little bad, Too much bad, finding a balance is the key.


Blood Work

My CBC results to be posted soon.


This thread will be edited (irrelevant or old posts deleted) as needed to maintain a high degree of quality postings.
maximus242
O_O holy sh*t, you guys know your drugs hu? well I have a few questions for you life, if you would indulge me ;D. Firstly can you give a description of what some of the brain nutritions do? it is also my understanding that nootropics can have some emotional side effects, what do you about this? nootropics and other drugs seem quite intresting, I assume the learning drugs aim to improve plasticity? anyways im intrested in learning more so if you could help me out it would be much appreciated biggrin.gif
noos
Hi LM, thanks for your post.
I have a question:
Hydergine 2.25-5 mg (w/f)
means with or without food? because manufacturers say take without food.
thanks
cerebral
take without food
shepard
I'm pretty sure his (w/f) means with fat.
code buttons
Life:
I live in the gulf coast and very close to Louisiana (as in Cajun Seafood), and my diet is a little heavy in sodium. I've always been interested in finding natural high sources of Potassium to counter-balance the high sodium intake. I know about bananas, but the high sugar and carb in them makes a little less than ideal. Any advise?
cerebral
use salt containing potassium chloride (mixed in with NaCl)
LifeMirage
QUOTE(code buttons @ Feb 27, 12:44 AM) *

Life:
I live in the gulf coast and very close to Louisiana (as in Cajun Seafood), and my diet is a little heavy in sodium. I've always been interested in finding natural high sources of Potassium to counter-balance the high sodium intake. I know about bananas, but the high sugar and carb in them makes a little less than ideal. Any advise?


Carrot juice or potassium salt.

QUOTE(noos @ Feb 26, 07:52 PM) *

Hi LM, thanks for your post.
I have a question:
Hydergine 2.25-5 mg (w/f)
means with or without food? because manufacturers say take without food.
thanks


I take it with food because in my case it causes mild nausea if i don't, otherwise take it on an empty stomach.
code buttons
Thanks for the quick response. I did forget to ask you something important: What's the proper Sodium to Potassium comsumption ratio for a healthy body assimilation?
code buttons
QUOTE(cerebral @ Feb 26, 11:28 PM) *

use salt containing potassium chloride (mixed in with NaCl)


Thanks for the tip, Cerebral
Trip like I do
Sweet...."Max Headroom"!
code buttons
QUOTE(Trip like I do @ Feb 27, 08:42 PM) *

Sweet...."Max Headroom"!


Some of us are not lucky enough to look like THE ONE, Trippy. So we have to find an avatar to hide out the physical challenges inheredited with the wrong genes. I figure I'll be beautiful enough after I get Singularized. Then I won't have any thing to hide!!!
OnlyNow
LifeMirage,
Amazing. Is this a full-time job? I assume you must take a complete daily inventory of your stock for an accurate accounting of what you have and what you're running low on. Besides the amount of time it must take to measure, regulate, purchase and research all of those supplements, it must take a substantial chunk out of your day just to ingest all of them. I try to take a multivitamin tablet daily. I have to talk myself into it, as the pill is large--which almost makes me gag. With this in mind, I wonder how you manage to get it all down? This is a serious question. I shudder to think of the cost, but if this regimen ehances the quality of your life, then I'm sure it's well worth it.


LifeMirage
QUOTE
LifeMirage,
Amazing. Is this a full-time job? I assume you must take a complete daily inventory of your stock for an accurate accounting of what you have and what you're running low on. Besides the amount of time it must take to measure, regulate, purchase and research all of those supplements, it must take a substantial chunk out of your day just to ingest all of them. I try to take a multivitamin tablet daily. I have to talk myself into it, as the pill is large--which almost makes me gag. With this in mind, I wonder how you manage to get it all down? This is a serious question. I shudder to think of the cost, but if this regimen ehances the quality of your life, then I'm sure it's well worth it.



It certainly feels like one.....yes i check and double check to insure the amounts are accurate. I take them throughout the day in both pill and powder form...a protein shake here and a water filled drink there. I do truly feel great on them and it took years to get here.
Jeff
What's your favorite nootropic/life extension drug, regarding actual effects, not based on long-term research?
LifeMirage
Piracetam/Deprenyl....but its a tough call.

Good question!!
Guest
it was one of these chemistry outfits like Sigma ( http://www.sigmaaldrich.com ). I forget the name but will dig it up.
LifeMirage
Personally I would not recommend that route.... several companies sell the trademark brand that is practically guaranteed high quality. IAS, QHI, UNI, Nubrain, Biogenesis, and more.

You really should have felt something at 50 mg or more….oh and it needs to be taken with food fyi.
Guest
maybe I'll give it another try. Thanks LM.
Jeff
I'm going to be testing N-Acetyl-L-Carnitine for a month or so (however a 750mg 120ct bottle lasts me), planning on using 1.5g daily, divided into two doses (1 before breakfast, and 1 before lunch), would this amount necessitate use of ALA or NAC? Is 1.5g even enough? I see some people use up to 8G!!!!! Good grief!

I figured I would post my own regimen (as far as supps/drugs go). Tell me what you think, if you don't mind...keep in mind that $ is going to be partly an issue from here on out.

NOW Vit-min 75+ Multi
Extra C (in form of ascorbic acid), E (in form of Dl-Alpha-Tocopherol-acetate) , B-6 (in form of pyridoxine hcl), Cal/Mag/Zinc (in forms of carbonate/oxide/gluconate) (w/f)
ZMA
Fish Oil 2g of EPA/DHA (w/f)
Piracetam 2.4-4.8g
Aniracetam 450mg-900mg (w/f)
Centrophenoxine 500mg (w/f)
Choline Bitartrate 5g
Pyritinol 400-800mg (w/f)
Vinpocetine 10mg (w/f)
Taurine 4-6g
CEE 3g
Bacopa 400mg
Wellbutrin XL 300mg
Hydergine 4.5mg
L-theanine, 300mg-600mg, if/as needed
Clonazepam, 1mg-4mg, if/as needed
Valerian Root, doses vary, if/as needed
N-Acetyl-L-Tyrosine, 800mg, if/as needed

When my centro, pyritinol, CEE, Bacopa, and N-Acetyl-L-Tyrosine run out, I'm not going to continue use. I've tried Alpha-GPC and haven't noticed any difference between that and choline bitartrate (except requiring different doses), so, I'm going to continue with choline bit. as my sole choline source. I have about 80 tablets of selegiline 5mg left, but, I'm not going to use until I finish perfecting my stack (and I'm in the Army, so, urinalysis is an issue). Also, I'm seeing an endocrinologist next week due to low test and free test levels.

My diet consists mainly of boneless skinless chicken breasts, lean red meats, Eggland's Best Eggs (vegetarian fed), almonds, natural peanut butter, skim milk, Light-N-Fit yogurt (sweetened with splenda), whey/egg protein powders, maltodextrin, natural almond granola, whole oats, long grain brown rice, 100% whole wheat spaghetti and bread, and flaxseeds on occassion. Occassionally canned tuna as well.

Goals - improve mood/alleviate depression/libido, improve focus, motivation, reduce anxiety (in forms of GAD and social), improve congitive function, and memory.
lucid_dream
I have heard about alcar and choline being a good combo, but phosphotidal choline (not as lecithin) is superior to choline bitartrate for ACh synthesis. And for alcar use the HCl kind and nothing else and make sure you take it on an empty stomach w lots of water.

No vasopressin?
Tone
YOu forgot to add a way to bcome undepressed so someone has enough energy and money to do all these things

Piracetam makes me feel like crap, hardcore, one of the worst drugs ever

"Deprenyl 1 mg (w/f)
Rasagiline 0.5 mg (w/f)"

why do you take both?? and how rich are you?
LifeMirage
QUOTE(tresbien @ Mar 04, 07:27 PM) *
QUOTE

Telomere Lengtheners:

Carnosine 1000 mg (w/f)


Lifemirage,

The above recommendation is remarkable. I am aware of only a single study (Shao L, Li QH, Tan Z. 2004) associating decreased telomere shortening with carnosine. How did you arrive at the dose of 1 gram?

Thanks in advance.


Based on the human research at Rush Medical Center in Chicago and LEF's dosing extrapolated from animal research. But i am slowly lowering my dose and increasing my N-Acetyl-L-Carnosine as time go by.



QUOTE(Tone @ Mar 04, 08:16 PM) *
YOu forgot to add a way to bcome undepressed so someone has enough energy and money to do all these things

Piracetam makes me feel like crap, hardcore, one of the worst drugs ever

"Deprenyl 1 mg (w/f)
Rasagiline 0.5 mg (w/f)"

why do you take both?? and how rich are you?


I continue to take deprenyl due to the massive research regarding its effects on aging and neuroprotection. However Rasagiline would appear to be more potent and has some unique effects. So i take both at the moment. Rich enough.

Tone
i take low dose selegiline but not everyday

my regimen is:

Tramadol, 50 mg + extra tramadol at times
Diphenhydramine every night to be able to go to sleep
Vitamins and Minerals, Saw Palmetto, Omega 3 but not daily,
Sometimes Kratom in place of Tramadol.

Wish list of things id like to take:

A ton of stablon every day
A microgram of naltrexone per day
A lot more tramadol if it had zero tolerance and dependance
LifeMirage
QUOTE
A ton of stablon every day



Doesn't everyone. biggrin.gif

Hey Hey
QUOTE(LifeMirage @ Mar 05, 06:25 AM) *

tresbien I suggest you search on Life Extension Foundation, Pubmed and any research cited by Rush Medical Center if you want more information on Carnosine, dosing, and telomeres.


Don't forget, you can die in auto accidents. Any drugs for that?
LifeMirage
QUOTE
Don't forget, you can die in auto accidents. Any drugs for that?


lol well now that you ask Hydergine is used as a drug in europe for accident victims and can help reduce the risk of death. Aside from that buckle up.

emolian
QUOTE(LifeMirage @ Mar 05, 01:15 PM) *

QUOTE
Don't forget, you can die in auto accidents. Any drugs for that?


lol well now that you ask Hydergine is used as a drug in europe for accident victims and can help reduce the risk of death. Aside from that buckle up.

hi, just out of interest, how much Hydergine would be a good subsistence dose to future-proof you for auto-accidents? smile.gif

also, about your regime, could you tell me:
why you don't take sulbutiamine (I heard it was really good),
where you get your CDP-choline from (I just can't find bulk powdered source anywhere),
and whether Advanced Research lithium orotate is a safe alternative to the AOR product (which I assume you take but which is quite expensive).

oh yes, im curious with all your knowledge and research what you think the primary cause of aging/brain aging is. A friend suggested cell membrane degredation, and so i was thinking PhosChol would be good for that.
I've also identified methylcobalamin and theanine as seemingly fairly important for mental health (as well as I think CDP-choline).
If you have time.
Thanks.
LifeMirage
QUOTE
hi, just out of interest, how much Hydergine would be a good subsistence dose to future-proof you for auto-accidents? smile.gif


Depends on your age.

QUOTE
also, about your regime, could you tell me:
why you don't take sulbutiamine (I heard it was really good),


Not really a very impressive cognitive compound and needs more studies in my opinion.

QUOTE
where you get your CDP-choline from (I just can't find bulk powdered source anywhere),
and whether Advanced Research lithium orotate is a safe alternative to the AOR product (which I assume you take but which is quite expensive).


I do not list my sources online, you may pm me for this information.

QUOTE
oh yes, im curious with all your knowledge and research what you think the primary cause of aging/brain aging is. A friend suggested cell membrane degredation, and so i was thinking PhosChol would be good for that. I've also identified methylcobalamin and theanine as seemingly fairly important for mental health (as well as I think CDP-choline).


That's a complicated answer covered thoroughly in my book. Centrophenoxine is one of the best compounds for maintaining healthy cell membranes.
emolian
QUOTE(LifeMirage @ Mar 16, 12:33 PM) *

That's a complicated answer covered thoroughly in my book. Centrophenoxine is one of the best compounds for maintaining healthy cell membranes.

What book is this? Can you give its name or ISBN number or something?
LifeMirage
Cognitive Awareness. Expected to be published this year.
noos
Good. Do you have the TOC?
Kane
QUOTE(LifeMirage @ Mar 16, 02:43 PM) *

Cognitive Awareness. Expected to be published this year.


And the author will be?
LifeMirage
QUOTE
Good. Do you have the TOC?


Yes but I won't post that online just yet


QUOTE
And the author will be?


Me...silly question.
OnlyNow
Have you published your book yet, LM?

I've been looking over your regimen. It's very interesting, but the list is quite long and complex for someone new to this. Can I ask--If you were restricted to pick 5 to 10 of these supplements, which ones would you choose? I don't think I saw a multiple vitamin on your list. Don't you take basic multiple vitamins? I also didn't see Omega 3 on the list. You don't think we need it? Also, I have a few questions about the skin stuff--why both idebenone and ubiquinol? Isn't idebenone a synthetic version of a component of coenzyme Q10? If so, then wouldn't it be redundant to also use CoQ10? Is the prescription Prevage a whole lot better than the otc version? Can you tell me what Aminocare cream does for the skin? Also do you have an opinion on routinely using Retin-A? I've seen a whole lot of good stuff about it--that it builds up collagen and prevents wrinkles. But I've also heard that tretinoin might keep the skin in a constant state of inflammation (which ultimately ages it). I don't know if there's any truth to that. You probably don't focus on skin as much as, say, a fortysomething woman (without naming names). But the fact that you use certain skin products makes me think you've done your research. Thanks!!!
LifeMirage
QUOTE
Have you published your book yet, LM?


Sigh. No with new research done daily and the full extent I would like to cover, my sundry projects (I'm working on creating monographs for 100's of drugs and supplements), articles, etc. I make have to wait another year.

QUOTE
I've been looking over your regimen. It's very interesting, but the list is quite long and complex for someone new to this. Can I ask--If you were restricted to pick 5 to 10 of these supplements, which ones would you choose?


An excellent multiple vitamin/mineral, a high quality EPA/DHA, R-Lipoic acid, Acetyl-L-Carnitine, L-Carnosine,

QUOTE
I don't think I saw a multiple vitamin on your list. Don't you take basic multiple vitamins?


I take both Ortho-Core by AOR and the Life Extension Mix by LEF. I take additional vitamins/minerals as needed.

QUOTE
I also didn't see Omega 3 on the list. You don't think we need it?


While I do get a fair amount of fish in my diet I do take epa/dha (omega 3's/fish oil). I believe everyone should consume fish and/or fish oil at least 3 times a week if not more.

QUOTE
Also, I have a few questions about the skin stuff--why both idebenone and ubiquinol?


Why not?

QUOTE
Isn't idebenone a synthetic version of a component of coenzyme Q10?


It is an analog of CoQ10 that while shares many properties has different effects.

QUOTE
If so, then wouldn't it be redundant to also use CoQ10?


No.

QUOTE
Is the prescription Prevage a whole lot better than the otc version?


Its somewhat better if you can afford it.

QUOTE
Can you tell me what Aminocare cream does for the skin?


For me it has increased my skin's moisture and elasticity. For more info:

http://www.naturalhealthconsult.com/Monographs/AminocareCream.html

QUOTE
Also do you have an opinion on routinely using Retin-A?


Never use by itself. Use it in very small dose 0.05%. Only 3-5 times a week max depending on your skin's state. I use it but did not list it. Time for an update.

QUOTE
I've seen a whole lot of good stuff about it--that it builds up collagen and prevents wrinkles. But I've also heard that tretinoin might keep the skin in a constant state of inflammation (which ultimately ages it). I don't know if there's any truth to that. You probably don't focus on skin as much as, say, a fortysomething woman (without naming names). But the fact that you use certain skin products makes me think you've done your research. Thanks!!!


My skin is pretty important to me so I do use a few select products I feel help make the difference. If you are considering using tretinoin be sure to use sunscreen and a good anti inflammatory serum (Idebenone, Carnosine, Lipoic acid).
OnlyNow
LM--Thank you so much for taking the time to answer all my questions. I see you've updated your info. I'm going back to work this week, so I'll need all the memory enhancements I can remember to take. I'll definitely pick up some of the supplements you recommended. (Apparently, all things beginning with "carn" and ending with "ine" are good.)

Not to focus on my appearance or anything, but on the skin regimen--can you tell me your routine? (I assume you don't use all products at once). What do you think of peptides (ie, Olay Regenerist or copper peptides)? Also, what kind of sunscreen do you use?

TIA

PS--What's a monograph?
LifeMirage
QUOTE
Not to focus on my appearance or anything, but on the skin regimen--can you tell me your routine? (I assume you don't use all products at once).


Honestly I use different ones daily depending on how my skin feels in the morning if that makes any sense.


QUOTE
What do you think of peptides (ie, Olay Regenerist or copper peptides)?


I think they have some benefit.


QUOTE
Also, what kind of sunscreen do you use?


I have a few i use. Solaris if i want to get a tan while protecting my skin, Otherwise LEF's TOTAL Sun Protection Cream. I also use LEF's Sun Protection Spray or LEP's Maui SolarMax (Rich Version) Spray at times.

QUOTE
PS--What's a monograph?


A technical article that goes into heavy details regarding a compound.

Flex
How do you feel about DHEA, particularly at my age? Namely 7-keto.

Where would your recomend getting LEF mix. All online sources I have found are pretty expensive... Including buying from LEFs webpage. I would love to try the product, but for $100 a month I am a bit hesitant.

What are your feelings on Stevia--I cook with Stevia all the time to drastically reduce calorie consumption while avoiding artificial sweeteners. My personal opinion is that it is just more government BS and lobbyists trying to preserve wealth by requiring stevia to be labeled as a "dietary supplement".

Lindsay
QUOTE(LifeMirage @ Aug 29, 2006, 01:23 PM) *
QUOTE
PS--What's a monograph?

A technical article that goes into heavy details regarding a compound.
LM, I just finished reading the posts in this thread. Very interesting information, you all! Thanks.

Talking about compounds: I came across this thread by Shawn, from way back in 2003. It about POTENTIALLY DANGEROUS SUPPLEMENTS: http://brainmeta.com/forum/index.php?showtopic=1958
How many are familiar with this list? Are there other compounds, which have come to the fore since then, which could be problematic? I am sure there are perhaps many even among prescribed drugs.

Interestingly, Shawn even mentioned an online source of supplements. Does this mean that it is okay for posters to say where we get our "secret", pocket-book friendly and healthy life-and-age enhancers? I do take several supplements which I will mention in another post. Though I am not adverse to taking prescribed drugs, when really needed, they--mostly in the form of herbs and enzymes--are the only "drugs". Should I mention where I get them? You can always send me a PM, if this is not allowed.

My health history: I was born in 1930, survived the depression, bad diet, several major childhood diseases, including rickets and diphtheria, was surrounded by relatives, several, including my mother, who died of TB--I was five--and other serious diseases.

Despite this, I was mostly healthy in high school and university. Once I got into my life's work I never lost one day, due to bad health, in over forty years.

Does this say something about the immune system? Who was it said: What does not kill you will make you stronger?

Check the next post.

maximus242
Intresting that you say that Lindsay, I had a somewhat similar experience.

For three months without end I was sick on and off, on and off. At times I couldnt get out of bed for a month, eventually it finally stopped. But something was diffrent when it did, philosophically I had a whole diffrent outlook on sickness. The strange thing is, I havent been sick ever since that time, ive been out in minus ten with shorts on and not even gotten a sniffel. Its been over two years now and I have yet to take any medicine, see a doctor or even have a stuffy nose.
Lindsay
Max, are there any research scientists with enough curiosity, and the resources, to do some reasearch on people like you, and me? If not, why not?

BTW, I have just up-dated my profile. To my interests I have added the following: Wouldn't it be nice if we all knew the best physical, mental and spiritual diet necessary for a full and abundant life. In addition, wouldn't it be nice if we were all made aware of the best way to die? That is, leave this three-dimensional universe, and move on to the next. Whatever it is.
maximus242
Best way to die? Prehaps death and life in itself is an illusion and the only death we see is another stage of life.

Drug companies use powerful advertising manipulation to make people feel sick on rainy and cold days, when infact the only thing you can get from the cold is ammonia. So why is it when winter hits that their is this sudden spike in cold products being bought - even though there is no reason for more people to be sick. Infact, technically speaking sickness rates should drop in the winter and rise in the summer. I find the great majority of sickness is percieved rather than biological, the sub-conscious can influence single cells. So if your consciousness were to believe it is becoming sick, the sub-conscious could fufill that thought by actually making you sick.
Flex
QUOTE(maximus242 @ Oct 31, 2006, 05:08 PM) *

Best way to die? Prehaps death and life in itself is an illusion and the only death we see is another stage of life.

Drug companies use powerful advertising manipulation to make people feel sick on rainy and cold days, when infact the only thing you can get from the cold is ammonia. So why is it when winter hits that their is this sudden spike in cold products being bought - even though there is no reason for more people to be sick. Infact, technically speaking sickness rates should drop in the winter and rise in the summer. I find the great majority of sickness is percieved rather than biological, the sub-conscious can influence single cells. So if your consciousness were to believe it is becoming sick, the sub-conscious could fufill that thought by actually making you sick.


Makes sense to me--maybe we all just suffer from media induced SAD (seasonally acquired depression, or seasonal affective disorder something like that )
Lindsay
maximus242 and Flex, thanks for the feedback, posted Today,
QUOTE
Max: Best way to die? Prehaps death and life in itself is an illusion and the only death we see is another stage of life....Flex: Makes sense to me--maybe we all just suffer from media induced SAD (seasonally acquired depression, or seasonal affective disorder something like that )


Because of a life-long interest in holistic health, back in the 1960's I began giving a lecture series under the general heading "Pneumatology--a study of the spirit". As part of the series, which lasted until I retired in 1994, in my lectures I always made the following point: Pneumatology--about studing the spirit, scientifically--is not about rejecting the useful information from all the sciences, including psychology and somatology, it is about integrating them as components of the spirit.

PSYCHOLOGY, THE REBELLIOUS CHILD OF PNEUMATOLOGY? THE WORD WAS FIRST USED BY PHILIP MELANCHTHON--LUTHERAN, REFORMER, HUMANIST, SCHOLAR
http://www.newadvent.org/cathen/10151a.htm

The word 'psychology' was first coined by Philip Melanchton, a humanist and modest, Lutheran. From 1550 to 1590, when it was first used in print, it was used--probably in parallel with pneumatology--the study of the spirit--to refer to the study of the soul/mind. It is also probable that the conflict between pneumatology and psychology came later.
==================================
MORE ON THE HISTORY OF PSYCHOLOGY
http://www.yorku.ca/christo/
http://psychclassics.yorku.ca/Krstic/marulic.htm
==================================
Interestingly, at the time (1964) I had no idea that the word, pneumatology, was actually already in the larger dictionaries. One dictionary I consulted, later, defined it as, "a branch of metaphysical philosophy popular in the sixteenth century" and studied in the great universities. Actually, it was the term used by those interested in studying the nature and function of the mind, in the spiritual sense********, before 'psychology' was coined, and popularized by the materialists such as Wilhelm Wundt and William James. Wundt, the founder of experimental psycholgy Wundt, the son of a Lutheran pastor, is credited with setting up the first laboratory of psychology at the university of Leipzig, in 1879. His goal it seems was to separate psychology from philosophy/pneumatology and to establish it as a science.
It is reported that he and his father had differences of opinion about the nature of the mind and whether or not there is such a thing as the spirit apart from the mind/brain.

There are historians who say that William James should share the credit for being one of the first "psychologists". Unlike Wundt, who he respected, he was profoundly interested in metaphysics--even spiritualism.

THE STREAM OF CONSCIOUSNESS(1892)
by William James
http://www.ship.edu/%7Ecgboeree/jamesselection.html

Take note: Before James, CHARLES PIERCE (1839-1914) http://www.peirce.org/ played an important role laying the linguistic foundation for the study of psychology, for which he got little credit during his lifetime. It is saidn that it was Charles Peirce who took Kant's idea that we can never really know the truth -- that all our beliefs are maybes -- and turned it into the basis for pragmatism, which, later, James popularized..

INFORMATION ABOUT WUNDT AND JAMES
http://www.ship.edu/~cgboeree/wundtjames.html
http://www.indiana.edu/~intell/wundt.shtml
http://www.indiana.edu/~intell/periodIndex.shtml#gs

When his work became known, many North American students, interested in the new science of psychology, went to Leipzig to study under Wundt for their doctorates. He was

Because of this, Wundt's work--which was basically rooted in materialism and atheism--had a profound influence on the educational systems of all of North America from then on. It is probably the basis for much of the conflict between religion and faith in our universities over the last number of decades. By the way, Wundt was the son of an evangelical Lutheran minister with whom he was in conflict. Could it be that this conflict was a root cause of his rebellion against organized religion.

This poses an important question: In the light of the recent article in the Wall Street Journal and re-printed in the Globe and Mail, is the tide beginning to turn?
==========================================================
HAS ANYONE HEARD OF THE MACE METHOD?
http://www.lilliput-information.com/wundt.html
http://members.iinet.com.au/~identiks/index.html
Flex
Another though--my common sense for the day. Winter=holidays, holidays=mass public gatherings in enclosed spaces i.e. malls. holidays also = family gatherings indoors. Not to mention kids at school no longer go outside for break because of the weather, adding to the spread of viruses etc.

The bottom line is that it is really common sense that in the winter people will be in close quarters with heaters circulating air. So unless these drug companies are behind Christmas, it is logical that the flu season is primarily cultural, and seasonal.

QUOTE
Infact, technically speaking sickness rates should drop in the winter and rise in the summer

Now I have a question... Are viruses effected by the weather? Since viruses are not a living organism it seems that they would not be, thus confirming the close quarters conclusion. I forget where exactly I read it, but I believe it was Paul Mahoney, who said that the protiens (I am assuming nucleic acids) will break down faster at room temp. than in the refridgerator. It seems like the cold weather would be better suited for preservation of viruses.
LifeMirage
QUOTE
How do you feel about DHEA, particularly at my age? Namely 7-keto.


That would depend on your age. I would not recommend taking DHEA unless you're either over 35 or your DHEA-S levels are lower than ideal levels. 7-KETO I would like to see more research done but it seems reasonably safe.

QUOTE
Where would your recomend getting LEF mix. All online sources I have found are pretty expensive... Including buying from LEFs webpage. I would love to try the product, but for $100 a month I am a bit hesitant.


Pm me for source recommendations.

QUOTE
What are your feelings on Stevia--I cook with Stevia all the time to drastically reduce calorie consumption while avoiding artificial sweeteners. My personal opinion is that it is just more government BS and lobbyists trying to preserve wealth by requiring stevia to be labeled as a "dietary supplement".


Safer than sugar. Which is all that really matters.

Flex
Two more quick question~ When taking vitamins and the likes is it alright to replace food with milk? I hate eating before 3:00 or so, but if I waited that long I would already be on my second round for the day. What are your feelings on NADH? I haven't found any reliable info on the subject. Would the effects be similar to CoQ10?
Zoolander
LifeMirages programs is an advanced program that basically includes "the works" so to speak. I would add a few more to his program but do not know what his blood work looks like

Agreed or disagreed LifeMirage?.....

The best place to start for beginners would be a good multivitamin/mineral + Good supply of fish oil + (young) antioxidants and/or (older) anti-carcinogenics

On top of this focus on the diet and decrease environmental toxins i.e chemicals in food and grooming products

Once you have put together a strong basic program get some blood work done. From here you can personalize your program accordingly

for example: high cholesterol
consider supplementing with:
flush free niacin (inositol hexonicotinate, IHN), and
phytosterols/stanols

Phytosterols/stanols are also effective at lowering elevated C-reactive protein (CRP) levels

QUOTE
Am J Clin Nutr. 2006 Oct;84(4):756-61.Click here to read

Reduced-calorie orange juice beverage with plant sterols lowers C-reactive protein concentrations and improves the lipid profile in human volunteers.

* Devaraj S,
* Autret BC,
* Jialal I.

Laboratory for Atherosclerosis and Metabolic Research and General Clinical Research Center, University of California Davis Medical Center, Sacramento, CA 95817, USA. sridevi.devaraj@ucdmc.ucdavis.edu

BACKGROUND: Dietary plant sterols effectively reduce LDL cholesterol when incorporated into fat matrices. We showed previously that supplementation with orange juice containing plant sterols (2 g/d) significantly reduced LDL cholesterol. Inflammation is pivotal in atherosclerosis. High-sensitivity C-reactive protein (hs-CRP), the prototypic marker of inflammation, is a cardiovascular disease risk marker; however, there is a paucity of data on the effect of plant sterols on CRP concentrations. OBJECTIVE: The aim of this study was to examine whether plant sterols affect CRP concentrations and the lipoprotein profile when incorporated into a reduced-calorie (50 calories/240 mL) orange juice beverage. DESIGN: Seventy-two healthy subjects were randomly assigned to receive a reduced-calorie orange juice beverage either without (Placebo Bev) or with (1 g/240 mL; Sterol Bev) plant sterols twice a day with meals for 8 wk. Fasting blood was obtained at baseline and after 8 wk of Placebo Bev or Sterol Bev supplementation. RESULTS: Sterol Bev supplementation significantly reduced total cholesterol (5%; P < 0.01) and LDL cholesterol (9.4%; P < 0.001) compared with both baseline and Placebo Bev (P < 0.05). HDL cholesterol increased significantly with Sterol Bev (P < 0.02). No significant changes in triacylglycerol, glucose, or liver function tests were observed with Sterol Bev. Sterol Bev supplementation resulted in no significant change in vitamin E and carotenoid concentrations. Sterol Bev supplementation resulted in a significant reduction of CRP concentrations compared with baseline and Placebo Bev (median reduction: 12%; P < 0.005). CONCLUSION: Supplementation with a reduced-calorie orange juice beverage containing plant sterols is effective in reducing CRP and LDL cholesterol and could be incorporated into the dietary portion of therapeutic lifestyle changes.

PMID: 17023701 [PubMed - indexed for MEDLINE]


My point?

Well rather than taking the full monty, get some blood work done and personalize the program to maximize your health. It's probably the cheaper method as well

lucid_dream
Resveratrol has received considerable media attention recently. Any recommendations, brand-wise? I know 100 mg or more per day is the suggested supplementation dosage.
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