BrainMeta.com Forum > Lifemirage's Antiaging-Cognitive Regimen

Zoolander

Nov 20, 2006, 02:13 AM

the biggest barrier with resveratrol supplementation is its bioavailability. Resveratrol is quickly glucoronidated into it's "in-active' metabolites. The current research is looking into whether these metabolites are active or not.

a great review from nature drug reveiws worth looking at

QUOTE

Nat Rev Drug Discov. 2006 Jun;5(6):493-506. Epub 2006 May 26.

Therapeutic potential of resveratrol: the in vivo evidence.

* Baur JA,
* Sinclair DA.

Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

Resveratrol, a constituent of red wine, has long been suspected to have cardioprotective effects. Interest in this compound has been renewed in recent years, first from its identification as a chemopreventive agent for skin cancer, and subsequently from reports that it activates sirtuin deacetylases and extends the lifespans of lower organisms. Despite scepticism concerning its bioavailability, a growing body of in vivo evidence indicates that resveratrol has protective effects in rodent models of stress and disease. Here, we provide a comprehensive and critical review of the in vivo data on resveratrol, and consider its potential as a therapeutic for humans.

PMID: 16732220 [PubMed - indexed for MEDLINE]

Even though resveratrol is quickly glucuronidated into it's inactive metabolites the above paper/review states that only small amounts are needed to benefit health

message me if you are interested in the full article

xanadu

Nov 20, 2006, 11:37 AM

All that "bioavailability" business overlooks the fact that benefits from resveratrol were first noticed in people who drank wine and ate grapes. The amounts ingested had to be no more than a few milligrams a day and were not in the form of extracts nor was it processed to make it more bioavailable. Despite those supposedly intractable barriers, people had much better health. One example of that is the "french paradox" in which they ate a fatty diet but did not have heart problems usually associated with that diet. It seems that the wine they drank did the job. Resveratrol levels in wine are variable and can be quite low yet they had good health. No 100 mg a day, just some wine and it did the job.

Hi Zoo

Zoolander

Nov 20, 2006, 09:30 PM

Hi Xanadu.

I totally agree. I made a point in my last post re. the bioavailability of resveratrol but also commented towards the end about the small amounts needed to benefit health.

It's all in the paper I quoted which I will make available to anyone who wishes to read it. Just message me

LifeMirage

Nov 22, 2006, 03:08 AM

QUOTE

Two more quick question~ When taking vitamins and the likes is it alright to replace food with milk? I hate eating before 3:00 or so, but if I waited that long I would already be on my second round for the day. What are your feelings on NADH? I haven't found any reliable info on the subject. Would the effects be similar to CoQ10?

As long as the milk contains fat.

NADH is interesting but I want to see more research before taking it on a regular basis.

Not quite.

LifeMirage

Nov 22, 2006, 03:14 AM

QUOTE

LifeMirages programs is an advanced program that basically includes "the works" so to speak. I would add a few more to his program but do not know what his blood work looks like

The list posted here only contains some.....not all of the compounds i take daily, weekly or monthly. When i have time I will update it.

QUOTE

Agreed or disagreed LifeMirage?.....

My regimen is created specifically for me over years of regular blood testing and considering my dietary intake. My nutritional-pharmaceutical intervention is intended to provide both antiaging and cognitive health support at a rather extreme level.

LifeMirage

Nov 24, 2006, 10:51 AM

Updated.

Flex

Nov 24, 2006, 11:29 AM

Why no pasteurized foods? And why no microwave? That would eliminate like half of my diet...

Zoolander

Nov 25, 2006, 06:49 AM

LifeMirage I noticed the following in your supplement regime

QUOTE

creatine 1gram

Do you load with creatine first? If so, how do you load? In an acute fashion or chronically over a month?

I have done extensive research with both creatine monohydrate and whey protein supplementation in aged males (60+ years) with and without resistance training. I should have several medical papers documenting my results published in the next 6 months.

I found with my research that it is important to make sure that the muscle is loaded correctly. Once loaded all that is needed to maintain the muscle loaded with creatine is to replace what is loast on a daily basis. The average daily loss of creatine is roughly 2 grams per day.

This brings me to my question.......is 1 grams per day of creatine adequate?

I do understand that you may not be taking creatine to increase basal PCr muscle stores. If so, what is the reasoning behind your creatine supplementation?

Zoolander

Nov 25, 2006, 07:07 AM

Flex,

QUOTE

Why no pasteurized foods? And why no microwave? That would eliminate like half of my diet...

sometimes you need to make sacrifices matey. Maintaining optimal health and preserving what you have for as long as possible requires comittment.

If you're not prepared to make changes/sacrifices in your quest to achieve certain goals then you need to ask yourself

"How important are the goals"

Diet is just one approach though. Minimising your exposure to environment toxins is important as well. This is all outlined in LifeMirages program.

I'm not sure if this has been mentioned but LifeMirage also takes supplements that are adaptogens. These adaptogens such as ashwagandha work via hormesis. Hormesis is the term for generally-favorable biological responses to low exposures of stressors. Some supplements actively stress both the physiological and psychological systems and in doing so stimulate an adaptive reponse to the stress. Hence the term adaptogen. It's a bit like going to the gym and working out. Your lifting a weight and applying a stress to the muscle. The muscle responds to the stress and comes back stronger. The same applies with adaptogenic supplements. Another very good adaptogenic supplement is Rhodiola Rosea

here are a few great papers on the topic

QUOTE

Mech Ageing Dev. 2004 Apr;125(4):285-9.
Aging, anti-aging, and hormesis.

* Rattan SI.

Department of Molecular Biology, Danish Centre for Molecular Gerontology, University of Aarhus, Gustav Wieds Vej, DK-8000 Aarhus-C, Denmark. rattan@imsb.au.dk

As a result of almost 50 years of efforts in collecting descriptive data, biogerontologists are now able to construct general principles of aging and to explore possibilities of gerontomodulation. Most of the data indicate that aging is characterized by a stochastic accumulation of molecular damage and a progressive failure of maintenance and repair, and the genes involved in homeodynamic pathways are the most likely candidate virtual gerontogenes. Several approaches are being tried and tested to modulate aging in a wide variety of organisms, but with the ultimate aim of improving the quality of human life in old age. These approaches include gene therapy, hormonal supplementation, nutritional modulation, and intervention by antioxidants and other molecules. A recent approach is that of applying hormesis in aging research and therapy, which is based on the principle of stimulation of maintenance and repair pathways by repeated exposure to mild stress.

PMID: 15063104 [PubMed - indexed for MEDLINE]

QUOTE

Phytother Res. 2005 Oct;19(10):819-38.

Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration.

* Panossian A,
* Wagner H.

Swedish Herbal Institute, Viktor Rydbergsgatan 10, SE-411 32 Gothenburg, Sweden. ap@shi.se

Plant adaptogens are compounds that increase the ability of an organism to adapt to environmental factors and to avoid damage from such factors. The beneficial effects of multi-dose administration of adaptogens are mainly associated with the hypothalamic-pituitary-adrenal (HPA) axis, a part of the stress-system that is believed to play a primary role in the reactions of the body to repeated stress and adaptation. In contrast, the single dose application of adaptogens is important in situations that require a rapid response to tension or to a stressful situation. In this case, the effects of the adaptogens are associated with another part of the stress-system, namely, the sympatho-adrenal-system (SAS), that provides a rapid response mechanism mainly to control the acute reaction of the organism to a stressor. This review focuses primarily on the SAS-mediated stimulating effects of single doses of adaptogens derived from Rhodiola rosea, Schizandra chinensis and Eleutherococcus senticosus. The use of these drugs typically generates no side effects, unlike traditional stimulants that possess addiction, tolerance and abuse potential, produce a negative effect on sleep structure, and cause rebound hypersomnolence or 'come down' effects. Furthermore, single administration of these adaptogens effectively increases mental performance and physical working capacity in humans. R. rosea is the most active of the three plant adaptogens producing, within 30 min of administration, a stimulating effect that continues for at least 4-6 h. The active principles of the three plants that exhibit single dose stimulating effects are glycosides of phenylpropane- and phenylethane-based phenolic compounds such as salidroside, rosavin, syringin and triandrin, the latter being the most active. Copyright © 2005 John Wiley & Sons, Ltd.

PMID: 16261511 [PubMed - indexed for MEDLINE]

LifeMirage, do you take Rhodiola??

Flex

Nov 25, 2006, 12:07 PM

QUOTE(Zoolander @ Nov 25, 2006, 07:07 AM)

Flex,

QUOTE

Why no pasteurized foods? And why no microwave? That would eliminate like half of my diet...

sometimes you need to make sacrifices matey. Maintaining optimal health and preserving what you have for as long as possible requires comittment.

If you're not prepared to make changes/sacrifices in your quest to achieve certain goals then you need to ask yourself

That still doesn't answer WHY

I understand you need to make changes, but I was wondering why exactly microwaved and pasteurized foods need to be avoided so much. I mean is there really that big of a difference between oat meal cooked on the stove, and cooked in the microwave?

As far as taking one gram of creatine, maybe it is because lifemirage eats plenty of raw, or lightly cooked fish?

maximus242

Nov 25, 2006, 01:11 PM

Flex, the reason is because processed food has the nutrients taken out of them when they are processed, they are put back in artifically afterwards but it isnt even close to the original benifits.

When food is processed they take all the good stuff out of it, try to put it back in, fail and then your left with a less healthy product.

Flex

Nov 25, 2006, 01:51 PM

QUOTE(maximus242 @ Nov 25, 2006, 01:11 PM)

Flex, the reason is because processed food has the nutrients taken out of them when they are processed, they are put back in artifically afterwards but it isnt even close to the original benifits.

When food is processed they take all the good stuff out of it, try to put it back in, fail and then your left with a less healthy product.

But how does denaturing a protien in the microwave differ from cooking it on the stove? Back to the oatmeal example...there doesn't appear to be any difference in the product produced in the microwave compared to the stove, except that you have to clean up a pot on the stove. Is there actually a big difference?

LifeMirage

Nov 26, 2006, 02:59 AM

QUOTE

That still doesn't answer WHY I understand you need to make changes, but I was wondering why exactly microwaved and pasteurized foods need to be avoided so much. I mean is there really that big of a difference between oat meal cooked on the stove, and cooked in the microwave?

A number of reasons.

Regarding microwave foods:

To avoid unnecessary high levels of AGEs (Advanced Glycation EndbyproductS) and radiolytic byproducts.

Regarding pasteurized foods:

To avoid unnecessary high levels of AGEs (Advanced Glycation EndbyproductS) and nutrition depleted foods.

Read more regarding this subject here.

LifeMirage

Nov 26, 2006, 03:04 AM

QUOTE

Do you load with creatine first? If so, how do you load? In an acute fashion or chronically over a month?

I have done extensive research with both creatine monohydrate and whey protein supplementation in aged males (60+ years) with and without resistance training. I should have several medical papers documenting my results published in the next 6 months.

I found with my research that it is important to make sure that the muscle is loaded correctly. Once loaded all that is needed to maintain the muscle loaded with creatine is to replace what is loast on a daily basis. The average daily loss of creatine is roughly 2 grams per day.

This brings me to my question.......is 1 grams per day of creatine adequate?

I do understand that you may not be taking creatine to increase basal PCr muscle stores. If so, what is the reasoning behind your creatine supplementation?

1 Gram daily is my current dosing of creatine on a daily basis. I take this based in part for the recent research on brain nutrition rather than muscle purposes.

LifeMirage

Apr 03, 2007, 10:12 PM

Updated for April.

mleach520

Apr 06, 2007, 09:01 AM

I am considering buying inositol. I can't PM you. Where do you buy your myo-inositol if you don't mind. If you would email me, I would appreciate it.

Your post says you take 5 grams. There is a * next to it. Does this mean you take 5 grams per month or do you take 5 grams per day?

I would really appreciate some help. Thanks.

LifeMirage

Apr 08, 2007, 02:26 PM

I take 5 grams a few times during the week.

You could not buy it from my source. I would suggest any company from the supplier list.

mleach520

Apr 10, 2007, 05:50 PM

QUOTE(LifeMirage @ Apr 08, 2007, 06:26 PM)

I take 5 grams a few times during the week.

You could not buy it from my source. I would suggest any company from the supplier list.

I plan on buying myo-inositol. When I search for places selling inositol I see things like:

IP-6 inositol
Inositol hexaniacinate
and just plain inositol

Since I am looking for myo-inositol and not any of the ones listed above, what should I do?

LifeMirage

Apr 13, 2007, 12:33 AM

I would inquire to the supplier what form they are selling or if they can order it.

mleach520

Apr 24, 2007, 03:19 PM

Which thyroid hormone is better for weight loss. T4 or T3?

LifeMirage

Apr 24, 2007, 04:37 PM

QUOTE

Which thyroid hormone is better for weight loss. T4 or T3?

Depends on the person.

mleach520

May 03, 2007, 07:01 PM

LifeMirage,

I began a Piracetam regimen a few days ago. Today I just completed day 4 and I feel absolutely no benefits from Piracetam. Here is what I have been doing:

6x800mg Piracetam tablets (2 in morning, 2 at lunch and 2 in the evening)
1x100mg 5-HTP morning
2x200mg CDP Choline (1 in morning, 1 in evening)
3x650mg inositol (3 in morning, 3 in evening)

On days 1 and 2, I had a whey protein shake with soy milk in the morning. On days 3 and 4 (yesterday and today) I had a soy protein shake with soy milk in the morning.

I have felt no benefits with Piracetam. All this stuff about being able to focus intensely. I feel no difference at all. Am I doing something wrong? Any suggestions? If I should not take Piracetam with a protein shake, can I take it with the other supplements?

LifeMirage

May 05, 2007, 02:42 AM

QUOTE

LifeMirage,

I began a Piracetam regimen a few days ago. Today I just completed day 4 and I feel absolutely no benefits from Piracetam. Here is what I have been doing:

6x800mg Piracetam tablets (2 in morning, 2 at lunch and 2 in the evening)
1x100mg 5-HTP morning
2x200mg CDP Choline (1 in morning, 1 in evening)
3x650mg inositol (3 in morning, 3 in evening)

On days 1 and 2, I had a whey protein shake with soy milk in the morning. On days 3 and 4 (yesterday and today) I had a soy protein shake with soy milk in the morning.

I have felt no benefits with Piracetam. All this stuff about being able to focus intensely. I feel no difference at all. Am I doing something wrong? Any suggestions? If I should not take Piracetam with a protein shake, can I take it with the other supplements?

Piracetam is one of the best overall cognitive enhancing and more importantly protecting nootropic you can take, however if you are looking to enhance one aspect of cognition namely focus in a very short time Piracetam would be a poor choice. While most nootropics start working in an hour not everyone notices the difference right away some people don't percept much of a difference at all.

Nothing you are taking should have any potent effect of focusing. I would suggest Nootropics that target that aspect more directly and potently such as Centrophenoxine, Pyritinol, Idebenone, L-Huperzine A, Deprenyl and more recently some people are responding to a new (yet old) compound called Phenylethylamine.

mleach520

May 22, 2007, 04:26 PM

LifeMirage,

I have 4 questions.

1. What is the difference between:
- Deprenyl Liquid (Cyprenil)
- Deprenyl Liquid (Selepryl)

2. Since MAO consumes PEA, and Deprenyl is a MAO inhibitor, then taking Deprenyl and PEA might
have a "doubling" effect. Is this safe, or is this too much?

3. What is the difference between reversible and irreversible MAO inhibitors? What are the consequences
of each?

4. Is it safe to combine the following 3 things:
- Deprenyl Liquid (Cyprenil) or Deprenyl Liquid (Selepryl)
- phenylethylamine (PEA)
- hydergine (liquid)

LifeMirage

May 22, 2007, 11:32 PM

QUOTE(mleach520 @ May 22, 2007, 07:26 PM)

LifeMirage,

I have 4 questions.

1. What is the difference between:
- Deprenyl Liquid (Cyprenil)
- Deprenyl Liquid (Selepryl)

2. Since MAO consumes PEA, and Deprenyl is a MAO inhibitor, then taking Deprenyl and PEA might
have a "doubling" effect. Is this safe, or is this too much?

3. What is the difference between reversible and irreversible MAO inhibitors? What are the consequences
of each?

4. Is it safe to combine the following 3 things:
- Deprenyl Liquid (Cyprenil) or Deprenyl Liquid (Selepryl)
- phenylethylamine (PEA)
- hydergine (liquid)

1. None really.
2. MAO-B breaks down several monoamines, taking PEA in high doses appears to overwhelm the enzyme and maintain higher levels of PEA for a period of time. Deprenyl has been studied with PEA in low doses safety for treating depression.
3. Obvious. I would only recommend reversible MAO-B inhibitors or the novel irreversible MAO inhibitor Deprenyl. Your brain needs balance and a natural cycle.
4. Yes, in low doses.

mleach520

May 23, 2007, 12:23 PM

3. What is the difference between reversible and irreversible MAO inhibitors? What are the consequences
of each?

3. Obvious. I would only recommend reversible MAO-B inhibitors or the novel irreversible MAO inhibitor Deprenyl. Your brain needs balance and a natural cycle.

I want to make sure I completely understand the difference between the reversible and irreversible MAO inhibitors. It sounds like irreversible MAO inhibitors (like deprenyl) will have a permanent effect. Is this true? If so, that would mean that you can take a certain amount of deprenyl and never have to take anymore ever again. But I can't imagine a drug that works like that. Are irreversible MAO inhibitors permanent?

xanadu

May 23, 2007, 02:49 PM

The microwave thing seems to be a matter of belief. Either you believe in the terrible effects of it or you don't. Any evidence seems to be sorely lacking. No evidence means that by default, MW should be considered safe.

LifeMirage

May 23, 2007, 11:28 PM

QUOTE(xanadu @ May 23, 2007, 05:49 PM)

The microwave thing seems to be a matter of belief. Either you believe in the terrible effects of it or you don't. Any evidence seems to be sorely lacking. No evidence means that by default, MW should be considered safe.

It's a personally choice for me. Although like other forms of high heat cooking it causes AGE formation higher than i prefer.

LifeMirage

May 23, 2007, 11:32 PM

QUOTE(mleach520 @ May 23, 2007, 03:23 PM)

3. What is the difference between reversible and irreversible MAO inhibitors? What are the consequences
of each?

3. Obvious. I would only recommend reversible MAO-B inhibitors. Your brain needs balance and a natural cycle.

I want to make sure I completely understand the difference between the reversible and irreversible MAO inhibitors. It sounds like irreversible MAO inhibitors (like deprenyl) will have a permanent effect. Is this true? If so, that would mean that you can take a certain amount of deprenyl and never have to take anymore ever again. But I can't imagine a drug that works like that. Are irreversible MAO inhibitors permanent?

Slight tweaking on my comments. Most irreversible MAO inhibitors should be avoid due to their actions on potentiating the catecholamine-releasing effect of tyramine, which raises blood pressure. Deprenyl is unique in regards to not sharing this effect common to irreversible MAO inhibitors.

bloodandsoil

Jun 06, 2007, 11:07 AM

QUOTE(LifeMirage @ Feb 25, 2006, 02:57 PM)

Lifemirage's Antiaging-Cognitive Regimen

Would you please explain your reason for not taking Alpha GPC? With the Cholinergics you are taking, I would think that you would need to increase the amount of choline precursors.

LifeMirage

Jun 06, 2007, 11:18 AM

QUOTE(bloodandsoil @ Jun 06, 2007, 02:07 PM)

QUOTE(LifeMirage @ Feb 25, 2006, 02:57 PM)

Lifemirage's Antiaging-Cognitive Regimen

Would you please explain your reason for not taking Alpha GPC? With the Cholinergics you are taking, I would think that you would need to increase the amount of choline precursors.

Cellular Membrane Agents

PPC (PhosChol, Lipostabil) 900 mg (w/f)
Centrophenoxine 500 mg (w/f)

Nootropics:

CDP-Choline (Citicoline) 500 mg
Alpha GPC 300 mg

Brain Nutrients:

L-Huperzine A 100 mcg (w/f)
Galantamine 4 mg (w/f)

Try reading my posts.

bloodandsoil

Jun 06, 2007, 11:35 AM

QUOTE(LifeMirage @ Jun 06, 2007, 11:18 AM)

Cellular Membrane Agents

PPC (PhosChol, Lipostabil) 900 mg (w/f)
Centrophenoxine 500 mg (w/f)

Nootropics:

CDP-Choline (Citicoline) 500 mg
Alpha GPC 300 mg

Brain Nutrients:

L-Huperzine A 100 mcg (w/f)
Galantamine 4 mg (w/f)

Try reading my posts.

My apologies. I'm just starting to learn about these subjects. I should have read over your post more carefully.

I have a couple follow-up questions, if you do not mind. How do you determine if your acetylcholine levels are oversupplied? How many acetylcholine facilitators do you recommend taking? You have 6 on your list, but I'm dubious as to whether you take them all at once or on an alternating basis. Thanks.

simon

Jun 08, 2007, 04:25 AM

I believe that Co-Q10 is used for gum health, is there any information regarding the effectiveness of idebenone for the same?
Thanks again for your constant up-dates.

LifeMirage

Jun 08, 2007, 12:54 PM

QUOTE(simon @ Jun 08, 2007, 07:25 AM)

I believe that Co-Q10 is used for gum health, is there any information regarding the effectiveness of idebenone for the same?
Thanks again for your constant up-dates.

No sad to say there is no published info on that matter thus I still take various CoQ10 products.

LifeMirage

Jun 08, 2007, 12:59 PM

QUOTE(bloodandsoil @ Jun 06, 2007, 02:35 PM)

QUOTE(LifeMirage @ Jun 06, 2007, 11:18 AM)

Cellular Membrane Agents

PPC (PhosChol, Lipostabil) 900 mg (w/f)
Centrophenoxine 500 mg (w/f)

Nootropics:

CDP-Choline (Citicoline) 500 mg
Alpha GPC 300 mg

Brain Nutrients:

L-Huperzine A 100 mcg (w/f)
Galantamine 4 mg (w/f)

Try reading my posts.

My apologies. I'm just starting to learn about these subjects. I should have read over your post more carefully.

I have a couple follow-up questions, if you do not mind. How do you determine if your acetylcholine levels are oversupplied? How many acetylcholine facilitators do you recommend taking? You have 6 on your list, but I'm dubious as to whether you take them all at once or on an alternating basis. Thanks.

Muscle tension, headaches, nausea, etc.
Depends on the person and why they are taking it.
Most of the items on my list I take throughout the day based on their halflives.

sgptexas

Jul 23, 2007, 08:46 AM

Where can I purchase ALT-711 (Alagebrium Chloride)? My father is in dier need of something to combat his atherosclerosis.

LifeMirage

Aug 10, 2007, 11:19 PM

QUOTE(sgptexas @ Jul 23, 2007, 11:46 AM)

Where can I purchase ALT-711 (Alagebrium Chloride)? My father is in dier need of something to combat his atherosclerosis.

Unavailable to the public.

LifeMirage

Sep 05, 2007, 05:42 PM

Just a note for the board I know I've spend little time here recently in part due to my workload in writing my books, monographs, and articles. I hope to have a certain amount finished within 2 months and start posting some of my material.

Flex

Sep 05, 2007, 08:24 PM

I can't wait! Let us know as soon as your books will be available--I know I will be one of the first to pick up a copy

LifeMirage

Sep 13, 2007, 10:39 PM

QUOTE(Flex @ Sep 05, 2007, 11:24 PM)

I can't wait! Let us know as soon as your books will be available--I know I will be one of the first to pick up a copy

Will do.

snikeris

Dec 21, 2007, 07:44 PM

Hi Lee,

I'm interested in your lipoic acid supplementation.

If you don't mind, I have several questions:

1) Why do you take both R-Lipoic Acid and R-Dihydrolipoic acid? From my limited research, it seems like R-Dihydrolipoic acid is superior and performs all the functions that R-Lipoic Acid does.

2) You say that you get your R-Lipoic Acid from na-rala/rala/rmct/sr. I haven't been able to figure out what rmct or sr means. Could you explain?

3) "from na-rala/rala/rmct/sr" seems to imply you are getting your R-Lipoic acid from multiple sources. Could you elaborate on all of the Lipoic Acid-type products you use? If you'd rather not disclose specific products on the board, could you please PM this information to me?

Thanks for your expertise on these boards.

Eagerly awaiting your response.

LifeMirage

Dec 21, 2007, 10:42 PM

QUOTE(snikeris @ Dec 21, 2007, 09:44 PM)

Hi Lee,

I'm interested in your lipoic acid supplementation.

If you don't mind, I have several questions:

1) Why do you take both R-Lipoic Acid and R-Dihydrolipoic acid? From my limited research, it seems like R-Dihydrolipoic acid is superior and performs all the functions that R-Lipoic Acid does.

2) You say that you get your R-Lipoic Acid from na-rala/rala/rmct/sr. I haven't been able to figure out what rmct or sr means. Could you explain?

3) "from na-rala/rala/rmct/sr" seems to imply you are getting your R-Lipoic acid from multiple sources. Could you elaborate on all of the Lipoic Acid-type products you use? If you'd rather not disclose specific products on the board, could you please PM this information to me?

Thanks for your expertise on these boards.

Eagerly awaiting your response.

1. They recycle each other after being oxidized hence best results are from taking both.
2. Rmct (R-Lipoic acid in medium chain triglycerides) and sr is sustained release.
3. Correct. You may pm me for exactly which products you are interested in.

snikeris

Jan 28, 2008, 01:11 PM

Hello again Lee,

I have a couple questions about your melatonin supplementation.

1) How did you settle on a daily dose of 1mg? Would you recommend this dose for a healthy adult (without any trouble falling asleep) for the purposes of antioxidant protection and increased quality of sleep?

2) When do you take it? An hour before bed? Right before bed?

3) Do you plan on taking this same dose every day, forever?

LifeMirage

Jan 30, 2008, 01:49 PM

Decylubiquinone added.

LifeMirage

Jan 30, 2008, 01:51 PM

QUOTE(snikeris @ Jan 28, 2008, 03:11 PM)

Hello again Lee,

I have a couple questions about your melatonin supplementation.

1) How did you settle on a daily dose of 1mg? Would you recommend this dose for a healthy adult (without any trouble falling asleep) for the purposes of antioxidant protection and increased quality of sleep?

2) When do you take it? An hour before bed? Right before bed?

3) Do you plan on taking this same dose every day, forever?

1. It's the dose I feel is right for me based on various personal reasons.
I believe 0.5-3 mg daily may be a good range for healthy adults.
2. Varies.
3. Varies but may increase as I get older.

random321

Mar 17, 2008, 11:07 AM

Hi, I just read this thread. Very good info.

Lee, is there any update on when your book will be released? I would love to buy it whenever it's ready.

LifeMirage

Mar 17, 2008, 03:43 PM

QUOTE(random321 @ Mar 17, 2008, 02:07 PM)

Hi, I just read this thread. Very good info.

Lee, is there any update on when your book will be released? I would love to buy it whenever it's ready.

Which one? I'm currently working on 3 books along with well over 100 monographs/articles so probably not til 2009 or 2010 at the soonest.

alphaiii

May 17, 2008, 12:28 PM

LifeMirage,

Just curious, why only 300mg of Benfotiamine? I know some studies looks at higher doses (Brownlee - 600mg).

Is there any reason not to take more than 300mg?

alphaiii

May 17, 2008, 12:40 PM

Do any of the other AGE inhibitors like Carnosine, Aminoguanidine, ect. actually have AGE-breaking ability?

LifeMirage

May 17, 2008, 03:11 PM

QUOTE(alphaiii @ May 17, 2008, 03:28 PM)

LifeMirage,

Just curious, why only 300mg of Benfotiamine? I know some studies looks at higher doses (Brownlee - 600mg).

Is there any reason not to take more than 300mg?

Studies using only benfotiamine do use higher doses. However the combination enhances their effect, thus a lower dose is effective. I don't take more than I need to.