Full Version: Biochemical Receptors
Presently, drug companies target about 500 known biochemical receptors in the human body, and that number is soon expected to jump as much as 20 fold to 10,000 targets.
....and in August 2004, major headlines in Britain announced that prozac had been found in UK drinking water.
....Evidence is mounting that many of the poisons that are polluting our waterways, our water supplies and our bodies are sourced from pharmaceutical drugs and personal care products....
It's a good thing you don't live in the USA where environmental pollution by corporate interests is sanctioned by the government.
I'd relish the opportunity to live in the states Rick. Contrary to Hey Hey's opinion, I am not anti-American. I would love the chance to intellectually mingle with my contemperaries on a wide range of issues surrounding the art world.
There's nothing like being and thinking with your own kind (artists that is), although there is something to be said about interdisciplinary endeavours. I've enjoyed numerous in depth conversations here and brainmeta and mindbrain, but am looking forward to getting back into the university atmosphere. Hey Rick, did I ever tell you that I was accepted into the Masters of Fine arts program at York University (www.yorku.ca) here in Toronto starting in September 2005?
Congratulations, Don. That should be very interesting and exciting.
rhymer here.
I've never heard anyone say anything bad about the USA (amongst my colleagues, family or friends).
I would love to visit but don't relish the time taken flying!
I really enjoy looking at various places using the worldwind software (though I've had several attempts to contact my computer by the DOD since I viewed a few airfields, including military ones).
I've never heard anyone say anything bad about the USA (amongst my colleagues, family or friends).
I would love to visit but don't relish the time taken flying!
I really enjoy looking at various places using the worldwind software (though I've had several attempts to contact my computer by the DOD since I viewed a few airfields, including military ones).
| QUOTE (Trip like I do @ May 26, 04:03 AM) |
| ....and in August 2004, major headlines in Britain announced that prozac had been found in UK drinking water. |
Trichlosan (commercial biocide) has been found in human breast milk and has been removed from products by many companies that initially incorporated it in such things as detergents, food wrappers and kitchen utensils.
So what do we do about these synthetic chemicals getting into the environment? Can we accept their presence if they are concentrations below the pharmacologically active levels? But sometimes accumulation occurs (e.g. DDT). Also, at non-pharmacological levels there could still be a risk of effects (e.g. through carcinogenic properties) with exposure over a long time period.
Should all new chemicals require certification to show that they can be removed from water supplies? Would this be feasible? Would this prevent the acceptance into use of potentially valuable pharmaceuticals?
In these drunken times in the UK, I think that prozac might usefully be added to beer! Only in sub-active levels, but calculated so that after 10 pints the active level has been reached.
Only government agencies have the authority to make the corporations behave responsibly regarding pollution of the environment and consumer product safety. Unfortunately in the USA the current administration is in bed with corporate short term interests. In the long term, of course, it's in the interests of corporations to behave responsibly, but they only look at their short term profit.
Corporations (companies) come and go - a bit like (biological) evolution. What's left over is the new environment for residual companies (analogous to species) to adapt to. Let's hope that there will always be residual companies.
Do you think that the pharmacutical (intellectually engineered) drugs introduced into the mainstream of today and of years past, via 'various means and mechanisms' are having an efficascious AFFECT on current spatio/temporal development , not only at the individual level but at the collective level as well? Are we being gently molded to perceive in a certain mode of thought?
I'm starting to sound like RTB (conspiracy theories etc.).
I'm starting to sound like RTB (conspiracy theories etc.).
QUOTE(Trip like I do @ May 25, 09:02 PM) 
Presently, drug companies target about 500 known biochemical receptors in the human body, and that number is soon expected to jump as much as 20 fold to 10,000 targets.
Fascinating!!
Heres a dream drug for you. Targets mu-1 as an agonist, not a totally full agonist but not partial either .. a mostly full agonist, has Zero affinity for any other receptor, does not affect metabolic pathways by induction or inhibition, and has a half life of 3 hours.
QUOTE(Trip like I do @ May 26, 01:49 PM)
I'd relish the opportunity to live in the states Rick. Contrary to Hey Hey's opinion, I am not anti-American. I would love the chance to intellectually mingle with my contemperaries on a wide range of issues surrounding the art world.
Indeed!
Taking nothing away from forums like these that serve as a bouncing board, to dialogue face to face
on any topic is a necessity to get to the nitty gritty of a matter.
Living in Asia is rewarding in many ways, but the lack of dialogue with others in my field who are English speakers is not one of them.
QUOTE(Trip like I do @ May 25, 07:02 PM)
Presently, drug companies target about 500 known biochemical receptors in the human body, and that number is soon expected to jump as much as 20 fold to 10,000 targets.
can someone produce a list of these 500 receptors? I didn't know there were so many.
the 500 probably includes many sub types e.g. CCK-1 CCK-2 , 5HT-1a, 5HT-2a
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