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> Acetyl l-Carnitine
Shawn
post Sep 28, 2003, 01:42 PM
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I'm curious what people's experiences have been with this, and whether they find it worthwhile. It's supposed to be taken on an empty stomach, usually 500 mg to 1 g, though I've safely taken 6 g. Given all the diverse supplements, this is one of the few that I think is actually worth taking, particularly if you don't have all the money in the world to spend on supplements.

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T_Tom_Terrible
post Oct 13, 2003, 12:47 PM
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I've noticed a very light effect on 1-2 grams, where I was able to enter a deeper state of hypnosis with greater ease. It's hard to describe, but there is a small but significant shift in my mental state.

I also have taken 500 mg - 1 g with 600 mg of Vinpocetine which produces a more pronounced alteration of consciousness. I usually smoked a very small amount of high grade cannabis with the above combination to achieve a somewhat hazy but prolonged high.

I just took 4 g on a full stomach, so I'll stop by here a bit later to elaborate on the effects.

Tom
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T_Tom_Terrible
post Oct 14, 2003, 10:24 PM
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Sorry that my methods are fairly unscientific...

A few hours after taking the 4 grams on a full stomach I could feel a change in my brain, just like on smaller amounts only amplified. I noticed some recurring time distortion which may have been magnified by the 4 g of Alcar. I have had some successful self induced time distortions (using NLP and self-hypnosis) previous to this one in the absence of any mind altering drugs but the time distortion I experienced on the 4 g of Alcar was unique.

Usually, when I choose to alter my perception of time my thoughts shift in tempo first and my sense of time is gradually affected in accordance. Basically, this is the most effective way I currently know how to do it. While I was on the 4 g of Alcar, however, my thoughts seemed to speed up while my perception of time seemed to slow down and could be sort of disorienting at times.

I don't know if this had to do with the Alcar at all, or if it had more to do with the other things I have been practicing lately - Taoist sexual techniques in conjunction with related self hypnosis sessions could have had more to do with it, but who knows?
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alcarman
post Oct 15, 2003, 03:54 AM
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Tom, it should work better if you take it on an empty stomach
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Guest
post May 08, 2004, 12:10 PM
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I have found that L-Carnitine gives me a very nasty case of the farts. When I stop taking it the farting ceases. Therefore, I feel it is the Carnitine that is doing it.
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Shawn
post May 08, 2004, 12:14 PM
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Guest, did you take 'L-Carnitine' or 'acetyl-l-carnitine' (aka ALCAR)? They're different things. I have heard that acetyl-l-carnitine is much better than l-carnitine, but I don't have the specifics about the difference onhand.
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David Tolson
post Jun 08, 2004, 11:56 AM
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I have been taking in the range of 1-4 g daily for just over a year. I have never noticed any subjective effects from it, although I wasn't looking for any. I think that it is definitely one of the few "must have" supplements.

There are many resources that indicate that there is a large difference between L-carnitine and acetyl-L-carnitine, but they are mistaken. They do play very different roles in the body, yes. However, supplemental acetyl-L-carnitine is rapidly deacetylated in the intestine yielding L-carnitine. The carnitine, whether it originated from ALCAR or L-carnitine, is reacetylated in various tissues later on. So supplementation with either will increase tissue levels of both. You will generally find ALCAR to be a lower price though.
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axiombiologicals
post Jun 24, 2004, 04:52 AM
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QUOTE (David Tolson @ Jun 08, 11:56 AM)
I have been taking in the range of 1-4 g daily for just over a year. I have never noticed any subjective effects from it, although I wasn't looking for any. I think that it is definitely one of the few "must have" supplements.

There are many resources that indicate that there is a large difference between L-carnitine and acetyl-L-carnitine, but they are mistaken. They do play very different roles in the body, yes. However, supplemental acetyl-L-carnitine is rapidly deacetylated in the intestine yielding L-carnitine. The carnitine, whether it originated from ALCAR or L-carnitine, is reacetylated in various tissues later on. So supplementation with either will increase tissue levels of both. You will generally find ALCAR to be a lower price though.

I had assumed that the larger doses were required to saturate the enzymes necessary for deacetylation, allowing for "acetyl-carnitine" to enter the bloodstream unchanged. Interesting.





Axiom Biologicals
Oxiracetam/Aniracetam/Pyritinol
http://home.comcast.net/~axiombiologicals
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aronhog
post Aug 20, 2007, 10:14 PM
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Acetyl L-Carnitine is an amino acid-like compound that is related to choline and may assist in the conversion of choline into acetylcholine.
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LifeMirage
post Sep 23, 2007, 08:02 AM
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N-Acetyl-L-Carnitine at 1,500-3,000 mg seem to have a potent effect on physical energy with a lesser effect on mental energy for me.
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Molitor
post Dec 08, 2007, 01:43 PM
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ALCAR is one of the non-vitamin/mineral supplements I've stuck with recently. I never got anything from a single dose, but taking about 500mg three times a day seems to decrease general fatigue over time. It's not stimulation, more like "I'm not as wiped out as I normally would have been."

I recently switched to PLCAR (propiony l-carnitine) to see how it compares. I've only been on it a couple days, but it seems like a sedative. I've been whooped for the past couple days, but I'm going to give it a trial of couple weeks. Any opinions on PLCAR? It doesn't seem to get much lovin'.

There's lots of goodies about ALCAR on PubMed (search for the full name "acetyl l-carnitine" or "propionyl l-carnitine". Here's a couple:

Carnitine v. Androgen

PLCAR v. ALCAR in Chronic Fatigue Syndrome

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carnitine
post Jul 07, 2016, 08:24 PM
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used as safe nutritional supplements in body building. L-Carnitine is usually available as L-Carnitine Fumarate and L-Carnitine L-Tartrate.
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Brain Hacker
post Dec 22, 2016, 02:49 PM
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It never did much for me, but I may of been dosing incorrectly.
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