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> Effect of nicotine on stims/noots
Wilber187
post Feb 24, 2017, 03:28 AM
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Hi guys, newbie to this forum! I'm just looking for clues as to why vaping appears to dull or pause the otherwise noticeable effects of piracetam, modafinil, lions mane and others. If I stop vaping, then the effects restart after 1-2 hours. I'm curious what the theory of action is here. I wondered if the nicotine stimulating the nicotinic receptors and or GABA might dampen acetylcholine production, but I'm too green in neuropharmacology to figure this out. Anyone have any thoughts please?

Many thanks!
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GodConsciousness
post Feb 24, 2017, 11:16 AM
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The nicotinic receptors may be doing a bit of an override.
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focusonthegood
post Sep 18, 2017, 01:42 PM
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I have found that nicotine and psychostimulants like Adderall interfere and cancel out the effects of less intense noots like Modafinil, leaving me feeling nothing at all rather than the effects of both drugs.

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