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> Interested but don't know where to look/research!
Androge
post Dec 29, 2016, 09:15 AM
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Hi together,

I wanted to write my master thesis in Neuroscience (studying Sportsscience) and the topic I was given (otherwise I couldn't start yet as no other profs where available) was to write a Review on how the motor cortices communicate, always including the primary motor cortex. So: How does the PMd, the PMv, the S1, the SMA and Basal Ganglia communicate with M1. I should provide the current state of research in terms of the mechanisms that underlie this communication on a physiological level.

Unfortunately all I find is studies on how these connections are traced (with retrograde tracers of rabies viruses etc.) and how these connections are organized, for instance only 30% of the cerebellum project to M1 which was found out doing this and that in macaque monkey etc.. I was just advised of looking at Peter Strick's (Pittsburgh) studies.. but from him I find most what I just listed.. not a single study on how the mechanism work.. I I should end up writing about 60-80 pages, so I'll probably need about 40 studies on that.. don't have a single one yet and don't wanna see my prof in that state, not to embarrass myself so I thought to first ask for advice here, maybe someone of you has an idea where to look in this respect.. Would be really grateful!! Thanks in advance!
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haohao
post Dec 30, 2016, 01:31 AM
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Hello Androge! Welcome to this forum to join in the academic communications. I'm not a Professor, and hope I could provide some suggestive opinions.

1. From your statement above, I thought you might need to browse some related motorially physiological on-line papers, try to list the related progress you had found though it might be not much, and propose your theories upon the mechanisms, which would be better if you had some proof to back you up. In addition, you might need the academic research of the neuro-signal system to widen your research paper.

2. I searched the Internet and found the following article : "Motor Cortex and Motor Cortical Interhemispheric Communication in Walking After Stroke: The Roles of Transcranial Magnetic Stimulation and Animal Models in Our Current and Future Understanding."(《Neurorehabilitation & Neural Repair》, 2015, 30(1):47-58) , which could be seen from xueshudotbaidudotcom with at least abstracts. Hope it may help you for reference. If you like, you could also see my poster published on this forum.

3. "Experience is one way to show your interest and span for the research, which has no direct links with the innovation and best practices. In my opinion, the continuing ability-based performance with interest is the key and the related recognition is important. I thought the essence of the education was the life-long learning and improvements, in which the so-called formal and regular education should be changed into the intensive and flexible learning aiming for the ability-based performances. To be a real intelligence neuroscientist or cognitive neuroscientist, you might need specialized ability-based performance and fund-included web-platform instead of a doctoral degree or post-doctoral medical background, or some professional training certificates or qualifications. "Learning and improving oneself is a life-long course. To be earnest, degrees and diplomas or occupational certificates or qualifications, even the web courses are totally not necessary to the research, even in the future. Internet, specialized e-contents and the interest for the research, including the practicing and webforum, is necessary." from one poster in this forum.
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Androge
post Jan 01, 2017, 08:16 AM
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Hi HaoHao,

first of all thanks for welcoming me and a happy new year to you!

Your advice seems very thoughtful to me, however I feel like there are still some questions open:

1. To be honest my interest goes towards neuroscience, neural mechanism of motor learning in general, where I want to develop a further understanding. This specific task of writing a Review about the "communication of several motor cortices with M1 and the mechanisms underlying this communication" comes from my Prof. I feel like I'm not yet on the right track on what the prof actually demands from me. However I think, when I work my self on the right track I think interest will increase by itself.

2. I am partly confused with the task to gather so far discovered "mechanisms" of the communication with M1 and how to fill 60 to 80 pages with this. After talking with my prof I was quite confident on finding many of these but after doing most part of my research, researching mostly keywords as "cortico-cortical communication" (found a review called "cortico-cortical communication dynamics" which didn't really help a lot although it sounded perfect)", "cortex connectivity" in connection with "primary motor cortex" etc., I mostly found, as I said, studies concerned with which cortices are connected to which, how this was shown, how the pathways are organized but not what mechanism these pathways/communications underlie. On the other side it appears to me as this is not treated or described in most studies , because (as you advised me on researching on neural-signal system) this always works the same, namely by the simple form of action potentials traveling over synapses by electric and biochemical processes, a basic mechanism already covered in simple school biology classes.

Or are there possibly other mechanism? Or do I simply have a misconception on "mechanism" in terms of neuroscience? (I did research about the word mechanism in biology of course)

3. The article you proposed sounded interesting and adequate at first glance, however I am not sure whether it is concerned with the mechanism of the communication, especially not focussing on connections with M1. However I could only find an abstract via my university page, so maybe I am wrong.

I can't contact my prof so soon as he is vacation, but I have the feeling that someone who is specialized in the field of neuroscience like you seem to be, may help me to eliminate basic misconceptions in this field, to guide me a bit in the right direction..

Thanks a lot already!

Androge
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haohao
post Jan 03, 2017, 12:35 AM
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Dear Androge,

Thank you for your opinions in the academic discussions above. I'm not a Professor, and hope I could provide some suggestive opinions.

1. From your statement above, the mechanism you referred to and interested could take the mechanism of the neuro-signaling system on the motor communications area into consideration, including the neural cognitive process and related chemical compound effects, which differs from the communications mechanism among the motor cortices around the primary motor cortex if the M1 in your post above refers to the primary motor cortex. The article I have recommended is surely “concerned with the mechanism of the communications” of the motor cortex (according to your statement) from xueshudotbaidudotcom, and could be expended into the topic you received though it focuses on the motor cortex as a whole. You might need to arrange another conservation with your professor bringing your academic research findings at a proper time via a scheduled email.

2. Currently the connectivity of the primary motor cortex in the area of the motor cortex, “pulse transcranial magnetic stimulation of the human motor cortex” and the bihemispheric motor cortical function as a whole are the main content and direction of the published on-line journal papers. So in some way, your interested research area could be innovative and research project supported, even some funding. I have published some posters on the neuroscience of the theories in this forum, including these of the neuro-signaling system. Hope them could be helpful. In addition, the word choice and its modifiers in the article title might be not always match the content of it, which is more concerned with the writing style. If you like, you could avoid it in your research outcomes publication in the future.

3.  "Experience is one way to show your interest and span for the research, which has no direct links with the innovation and best practices. In my opinion, the continuing ability-based performance with interest is the key and the related recognition is important. I thought the essence of the education was the life-long learning and improvements, in which the so-called formal and regular education should be changed into the intensive and flexible learning aiming for the ability-based performances. To be a real intelligence neuroscientist or cognitive neuroscientist, you might need specialized ability-based performance and fund-included web-platform instead of a doctoral degree or post-doctoral medical background, or some professional training certificates or qualifications. "Learning and improving oneself is a life-long course. To be earnest, degrees and diplomas or occupational certificates or qualifications, even the web courses are totally not necessary to the research, even in the future. Internet, specialized e-contents and the interest for the research, including the practicing and webforum, is necessary." from one poster in this forum.
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