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> Brain Damage From Cognitive Enhancers, My brother lost his mind by following the advice posted on this website.
Flex
post Jul 12, 2012, 03:40 PM
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In other more important news, anyone interested in a free for all of questions have at em. It is actually going to be fun for me to piece everything back together and I look forward to doing so on this forum, a great place to grow and discover bother who you are and who you will become.

Oh btw nootropics have nothing to do with my breakdown. I am going to try to get a complete drug test from my doctor when I see her Friday. I can verify that the 3 days leading up to the event I took 5,10 and then 50mg of pregnenolone, so it was either triggered by marijuana withdrawals (I doubt) pregnenolone (I doubt) or my own brain turning in on itself (most likely). Hard to escape biology. Maybe I was just born to be a bit volatile at times--nothing wrong with that--plenty of people are.
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post Jul 12, 2012, 07:44 PM
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Just make sure and don't check-in at THE "Hotel California"!
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post Jul 13, 2012, 06:34 AM
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QUOTE(Flex @ Jul 13, 2012, 12:40 AM) *

I can verify that the 3 days leading up to the event I took 5,10 and then 50mg of pregnenolone, so it was either triggered by marijuana withdrawals (I doubt) pregnenolone (I doubt) or my own brain turning in on itself (most likely). Hard to escape biology. Maybe I was just born to be a bit volatile at times--nothing wrong with that--plenty of people are.

Pregnenolone has excitatory properties:
http://www.ncbi.nlm.nih.gov/pubmed/20816925
But it looks really good for neurogenesis and plasticity provided you keep a low dose (50mg is not a low dose) and donīt mix it with other supplements that can increase bioavailability like MSM. I am really interested though.

Anyway, as you said maybe was just meant to happen sooner or later. For many of us full mental stability is more of a mask or a pretension than a reality.



Donīt be nasty with Ronnie. All his anger was just a manifestation of love and love can be a terrible thing. God I bet he would have set in fire BM server if he had the chance. In so many ways he remind me to Alexander the great when he found out Hephaestion was dead:

http://en.wikipedia.org/wiki/Hephaestion
QUOTE
Plutarch says that, being a young man and a soldier, Hephaestion had ignored medical advice, and as soon as his doctor, Glaucias, had gone off to the theatre, he ate a large breakfast, consisting of a boiled fowl and a cooler of wine, and then fell sick and died.[66]

Hephaestion's death is dealt with at greater length by the ancient sources than any of the events of his life, because of its profound effect upon Alexander. Plutarch says "... Alexander's grief was uncontrollable ..." and adds that he ordered many signs of mourning, notably that the manes and tails of all horses should be shorn, the demolition of the battlements of the neighbouring cities, and the banning of flutes and every other kind of music.[68] Arrian relates an account that "... he flung himself on the body of his friend and lay there nearly all day long in tears, and refused to be parted from him until he was dragged away by force by his Companions ...",[69] another that said "... he lay stretched upon the corpse all day and the whole night too ...",[69] and another which told how he had the doctor, Glaucias, executed for his lack of care.[70] Arrian also mentions Alexander ordering the shrine of Asclepios in Ecbatana to be razed to the ground,[71] and that he cut his hair short in mourning,[72] this last a poignant reminder of Achilles' last gift to Patroclus on his funeral pyre: "... he laid the lock of hair in the hands of his beloved companion, and the whole company was moved to tears."[73]

Another hint that Alexander looked to Achilles to help him to express his grief may be found in the campaign which shortly followed these events, against a tribe called the Cossaeans. Plutarch says they were massacred as an offering to the spirit of Hephaestion, and it is quite possible to imagine that to Alexander, this might have followed in spirit Achilles' killing of "... twelve high-born youths ..." beside Patroclus' funeral pyre.[68]

Arrian states that all his sources agree that "... for two whole days after Hephaestion's death Alexander tasted no food and paid no attention in any way to his bodily needs, but lay on his bed now crying lamentably, now in the silence of grief."[74] Alexander ordered a period of mourning throughout the empire, and Arrian tells us that "Many of the Companions, out of respect for Alexander, dedicated themselves and their arms to the dead man ..."[75] The army, too, remembered him; Alexander did not appoint anyone to take Hephaestion's place as commander of the Companion cavalry; he "... wished Hephaestion's name to be preserved always in connexion with it, so Hephaestion's Regiment it continued to be called, and Hephaestion's image continued to be carried before it."[76]

Alexander sent messengers to the oracle at Siwa, to ask if Amon would permit Hephaestion to be worshipped as a god. When the reply came, saying he might be worshipped not as a god, but as a divine hero, Alexander was pleased, and "... from that day forward saw that his friend was honoured with a hero's rites."[77] He saw to it that shrines were erected to Hephaestion's memory, and evidence that the cult took hold can be found in a simple votary plaque now in Archaeological Museum of Thessaloniki, inscribed, "To the Hero Hephaestion".[78]

Maybe we should call ourselves 'the Cossaeans'...
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Tone
post Jul 13, 2012, 07:33 AM
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Some of the more potentially dangerous Nootropics are:

Huperzine
Selegiline
Racetams can be aggravating when combined with others or having a pre existing mental condition

The most easily handled is Tianetpine, Brandname Stablon. No one knows why its so non-toxic considering it's has a tricyclic base. Once its fatty tail is beta-oxidized it seems to be a stable inert compound that does nothing while excreting. before being oxidized, it seems to do nothing other than lower AMPA, raise dopamine, lower serotonin, all with a limited ceiling effect.
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Tone
post Jul 13, 2012, 07:40 AM
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QUOTE(Flex @ Jul 12, 2012, 06:40 PM) *

In other more important news, anyone interested in a free for all of questions have at em. It is actually going to be fun for me to piece everything back together and I look forward to doing so on this forum, a great place to grow and discover bother who you are and who you will become.

Oh btw nootropics have nothing to do with my breakdown. I am going to try to get a complete drug test from my doctor when I see her Friday. I can verify that the 3 days leading up to the event I took 5,10 and then 50mg of pregnenolone, so it was either triggered by marijuana withdrawals (I doubt) pregnenolone (I doubt) or my own brain turning in on itself (most likely). Hard to escape biology. Maybe I was just born to be a bit volatile at times--nothing wrong with that--plenty of people are.


Stay away from all cholinergics & AMPA boosters, regardless of the cause, You need basic nutrition and meditation. Stay away from benzos unless a doctor already gave you them and its too late. Ask a doctor about Trileptal
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Tone
post Jul 13, 2012, 07:46 AM
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I have never been into nootropics, they aggravate me and make me dysphoric. I can already recite you PI to the nearest 50th digit just because a banner of it was in 10th grade class room.
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Flex
post Jul 13, 2012, 01:54 PM
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Almost killed myself twice on deprenyl. Once when in combination with PEA and once in combination with a nicotine (not a smoker, got passed a blunt and didn't even think about it).
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Tone
post Jul 13, 2012, 02:47 PM
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Youre supposed to take only 1 mg once every 3 days as a brain protector that people do because there's only a few dozen thousand dopamine neurons in the brain and its the life-limiting factor of the brain. Its irreversible, the body's manufacturing of new MAO-B must match or exceed the rate of inhibition or else inhibition will accumulate, making scores of drugs dangerous in interaction. Of course now you should not even do that, and instead take none.

An alternative non-psychoactive brain protector is R-Alpha Lipoic Acid, 100 mg
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Flex
post Jul 13, 2012, 02:52 PM
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I never really took more than that, but got some nasty side effects in combo with externals. I think it is best for the elderly smile.gif No need to rush the brain saving lol. I will probably give it another try around 55-60.
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Tone
post Jul 13, 2012, 02:59 PM
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I wish that things like Selegiline + PEA worked, but they dont and are just cheap stimulants. We should get Tianeptine over the counter in all countries but that would put billions of pharmaceuticals out of business. Im not saying it would replace all drugs, an example is that even a person taking a cocktail of 5 different drugs might be able to drop 3 of them in favor of tianeptine, leaving only 2 scripts left. The net loss to pharma would be bigger than any other loss of you had Tianeptine over the counter.

Obviously it could be over the counter considering its safer than Advil, Benedryl, tylenol & Nyquil, some of these which have lead to many unspoken of deaths. Its just a matter of The big Pharma business and CIA-Driven Street Drug Business that it would cut into deeply. It would do this because it would cut down on the amount of drugs one would want to take to either medicate or self-medicate. You can bet a person on Tianeptine would use less drugs than a person not on Tieneptine, in almost all cases with their being a minority of exceptions.
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Tone
post Jul 13, 2012, 03:08 PM
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whatever you got will go away with time, The brain repairs far more than is currently admitted. The brain will just rewire and regroup to compensate. It is largely genetic disorders that remain permanent. Youll fully recover, youll see
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Flex
post Jul 13, 2012, 04:28 PM
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I am not worried, I just wish I took record of all the good ideas that sprung up smile.gif I should have file for like 20 patents...
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Tone
post Jul 13, 2012, 05:12 PM
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Did you take hydergine at all, and if so what did it do?

Can you say what your diagnosis was, they just dont know what happened and gave you anti-psychotics ? That standard procedures is to scratch ones head, then order an injection of haldol or thorazine, Then, to the relatives, give off an aura that you are a doctor and know what you are doing.
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Flex
post Jul 14, 2012, 01:01 PM
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Have taken hydergine in the past, and it doesn't do shit (noticeably anyhow) it is just like piracetam for me (also does nothing noticeable).

I think they basically just made shit up. Bipolar type 1 with cannabis induced psychosis. I stopped smoking weed like 3 days before I went "manic" but I was acting weird before that. I quit smoking because I felt weird, so it is pretty bs in my eyes. 4 shots of thorazine in the ass were definitely ordered though lol.
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Tone
post Jul 14, 2012, 01:07 PM
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Ive heard enough from people, Im not going to buy Hydergine, its too inactive. Its another dead end in a search for symptoms relief after already having seen 10 doctors.
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Flex
post Jul 14, 2012, 01:15 PM
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What symptoms exactly? NADH can relieve just about anything for me.
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KoolK3n
post Jul 14, 2012, 03:37 PM
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QUOTE(Flex @ Jul 14, 2012, 04:01 PM) *

I think they basically just made shit up. Bipolar type 1 with cannabis induced psychosis. I stopped smoking weed like 3 days before I went "manic" but I was acting weird before that. I quit smoking because I felt weird, so it is pretty bs in my eyes. 4 shots of thorazine in the ass were definitely ordered though lol.


What is your lithium dosage? Can you no longer drink caffeine? Decaf green tea all the way.
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Tone
post Jul 14, 2012, 04:32 PM
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QUOTE(Flex @ Jul 14, 2012, 04:15 PM) *

What symptoms exactly? NADH can relieve just about anything for me.


Doesnt do a thing
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Flex
post Jul 14, 2012, 07:40 PM
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QUOTE(Tone @ Jul 14, 2012, 05:32 PM) *

QUOTE(Flex @ Jul 14, 2012, 04:15 PM) *

What symptoms exactly? NADH can relieve just about anything for me.


Doesnt do a thing


As a biochemist (almost, UCLA 2009-present) I can tell you right off that is a lie. If you must feel it to believe it, try 20mg sublingually one time (btw I do not recommend people take more than 5-10mg on occasion, unprofessional opinion). It may even be added to the WADA list in the near future for you Olympics fans.
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Flex
post Jul 14, 2012, 07:45 PM
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QUOTE(KoolK3n @ Jul 14, 2012, 04:37 PM) *

QUOTE(Flex @ Jul 14, 2012, 04:01 PM) *

I think they basically just made shit up. Bipolar type 1 with cannabis induced psychosis. I stopped smoking weed like 3 days before I went "manic" but I was acting weird before that. I quit smoking because I felt weird, so it is pretty bs in my eyes. 4 shots of thorazine in the ass were definitely ordered though lol.


What is your lithium dosage? Can you no longer drink caffeine? Decaf green tea all the way.


For now:
1.5g Divalproex a day in divided doses
1.5g Lithium per day divided doses
500mg Chlorpromazine divided
.5mg Clonazepam for sleep as needed

Much less in the near future I hope. My lithium levels are fine with my usual amount of caffeine so no concern. You only have to watch out if you change your routine drastically. Like if I were to have 7 cups of coffee for the next few days I might have to worry smile.gif
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Tone
post Jul 15, 2012, 07:03 AM
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QUOTE(Flex @ Jul 14, 2012, 10:45 PM) *

QUOTE(KoolK3n @ Jul 14, 2012, 04:37 PM) *

QUOTE(Flex @ Jul 14, 2012, 04:01 PM) *

I think they basically just made shit up. Bipolar type 1 with cannabis induced psychosis. I stopped smoking weed like 3 days before I went "manic" but I was acting weird before that. I quit smoking because I felt weird, so it is pretty bs in my eyes. 4 shots of thorazine in the ass were definitely ordered though lol.


What is your lithium dosage? Can you no longer drink caffeine? Decaf green tea all the way.


For now:
1.5g Divalproex a day in divided doses
1.5g Lithium per day divided doses
500mg Chlorpromazine divided
.5mg Clonazepam for sleep as needed

Much less in the near future I hope. My lithium levels are fine with my usual amount of caffeine so no concern. You only have to watch out if you change your routine drastically. Like if I were to have 7 cups of coffee for the next few days I might have to worry smile.gif



Thats so stupid, you should have been given Trileptal instead of lithium, Ripserdal instead of Thorazine, 22.5 mg Temezepam caps for sleep instead of the other benzo. Long half life benzos with active metabolites are not for insomnia let alone initial insomnia for F**K sake. they always do this. You are going to be on that benzo for life or have a terrible time withdrawing comared to tamazepam which degrades into nothing every day. They think youll have interdose-rebound anxiety or like the temezepams feeling. You should be given 12 temezepam a month, 30 trazadone and instructed to use the temezepam once every 3 nights, with the trazadone being the med for the 2 nights between.
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Tone
post Jul 15, 2012, 07:16 AM
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QUOTE(Flex @ Jul 14, 2012, 10:40 PM) *

QUOTE(Tone @ Jul 14, 2012, 05:32 PM) *

QUOTE(Flex @ Jul 14, 2012, 04:15 PM) *

What symptoms exactly? NADH can relieve just about anything for me.


Doesnt do a thing


As a biochemist (almost, UCLA 2009-present) I can tell you right off that is a lie. If you must feel it to believe it, try 20mg sublingually one time (btw I do not recommend people take more than 5-10mg on occasion, unprofessional opinion). It may even be added to the WADA list in the near future for you Olympics fans.


Well for a person like me nothing short of an Amineptine-like or Oxycodone-like drug is going to do anything to my mind state or functioning. Im serious. Psychiatrists, FDA, american psychiatric association, and other people are not serious about feeling better, improving dysphoria, chronic fatigue or depression-like disorders, they are all weak minded and softcore with a loser attitude in terms of which drugs to use, because they dont suffer. I dont F**K around with bullshit and would get my brain wire-headed with electrodes if it were available and safe
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Tone
post Jul 15, 2012, 07:19 AM
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there is no seriousness in treating depression spectrum disorders, no sense of urgency or seriousness. All weak minded. If someone breaks a leg and is screaming, there is a serious solution, injection with morphine in the ambulence followed by a vicodin script. But depression, they arent serious and keep F**KING around with BS for 60 years
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Flex
post Jul 15, 2012, 09:49 AM
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I would be scared if they tried to help smile.gif Research is basically performed on patients in real time. Drug companies don't want to touch psycho-shit because there is no good way to. If they could figure out something better than exercise and diet, they sure as hell would go for it. Maybe if patents were extended for psychotropic shit to 30-40 years there would be more incentive.
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still
post Jul 25, 2012, 08:00 AM
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QUOTE(Flex @ Jul 15, 2012, 01:49 PM) *

I would be scared if they tried to help smile.gif Research is basically performed on patients in real time. Drug companies don't want to touch psycho-shit because there is no good way to. If they could figure out something better than exercise and diet, they sure as hell would go for it. Maybe if patents were extended for psychotropic shit to 30-40 years there would be more incentive.


So what was the breakdown like? It's good to see you seem to be functioning again. It sounded like you were a vegetable for a while. Was it a feeling that kept you from functioning? Apathy? Fear? A seemingly physical inability to act in accordance with your thoughts / desires, such as overwhelming fatigue? Scrambled thoughts? A disconnect between your thoughts and their transformation into practical action?
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post Jul 25, 2012, 10:47 AM
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Hello, I just want to say something about this discussione.Tone says that huperzine is dangerous ...... for me this is wrong, I ask in the tone of scientific study which proves that it is dangerous? I take the huperzine from 3 months to 400 mcg per day, although I have not found any side effects, and also true that I have not noticed big benefits in memory, but only high concentrations. The racetams are known to have interactions, but it is very difficult, piracetam is the safest thing in the world. That is all that can be dangerous drugs such as deprenyl, adderall, MAOI inhibitors, etc.. Or all possible interactions. For example, if you take yohimbine with some supplements, like many pre-wprkout that are out there and then at the same time you eat foods containing tyramine much, you risk a heart attack!
xflex
I am not sure but I think that the explanation for your problem is easy ...... the pregnelone is not dangerous per se, but should not be underestimated, therefore, that concerns the interactions that may have ..... in fact it can substances in your body to absorb more than 400% of what would happen without his recruitment. In fact, in many supplements, do not take any medicine while using the pregnelone. Your problem is that when thou hast taken, you have also smoked the crap that absolutely no knowledge.
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Flex
post Jul 25, 2012, 11:12 AM
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QUOTE(still @ Jul 25, 2012, 09:00 AM) *

QUOTE(Flex @ Jul 15, 2012, 01:49 PM) *

I would be scared if they tried to help smile.gif Research is basically performed on patients in real time. Drug companies don't want to touch psycho-shit because there is no good way to. If they could figure out something better than exercise and diet, they sure as hell would go for it. Maybe if patents were extended for psychotropic shit to 30-40 years there would be more incentive.


So what was the breakdown like? It's good to see you seem to be functioning again. It sounded like you were a vegetable for a while. Was it a feeling that kept you from functioning? Apathy? Fear? A seemingly physical inability to act in accordance with your thoughts / desires, such as overwhelming fatigue? Scrambled thoughts? A disconnect between your thoughts and their transformation into practical action?


It is very difficult to describe. It is almost as if the world became a movie set and everything was placed there for me alone to interact with. I definitely became very paranoid about completely irrational nonsense and then I went from zero to hobo in about two days. I honestly cannot remember more than little snippets from my birthday (May 15) up to the 4th of July. It was basically analogous to being on a month long acid trip that just never stopped. Much of it was just hyper imagination and being able to see things in very creative ways, but I distinctly remember several full blow hallucinations, things that just could not possibly be real.
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post Jul 26, 2012, 04:58 PM
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QUOTE(Flex @ Jul 25, 2012, 11:12 AM) *

QUOTE(still @ Jul 25, 2012, 09:00 AM) *

QUOTE(Flex @ Jul 15, 2012, 01:49 PM) *

I would be scared if they tried to help smile.gif Research is basically performed on patients in real time. Drug companies don't want to touch psycho-shit because there is no good way to. If they could figure out something better than exercise and diet, they sure as hell would go for it. Maybe if patents were extended for psychotropic shit to 30-40 years there would be more incentive.


So what was the breakdown like? It's good to see you seem to be functioning again. It sounded like you were a vegetable for a while. Was it a feeling that kept you from functioning? Apathy? Fear? A seemingly physical inability to act in accordance with your thoughts / desires, such as overwhelming fatigue? Scrambled thoughts? A disconnect between your thoughts and their transformation into practical action?


It is very difficult to describe. It is almost as if the world became a movie set and everything was placed there for me alone to interact with. I definitely became very paranoid about completely irrational nonsense and then I went from zero to hobo in about two days. I honestly cannot remember more than little snippets from my birthday (May 15) up to the 4th of July. It was basically analogous to being on a month long acid trip that just never stopped. Much of it was just hyper imagination and being able to see things in very creative ways, but I distinctly remember several full blow hallucinations, things that just could not possibly be real.


Sounds to me as a mentally breakdown in general, with the cognition supplements just as catalyst. I just dont get it, you guys do some experiments with the most important thing you have,your mind, with no ideas of the hidden coming side effects. I cannot imagine the situation someone must be to take that risk with a real sense. Your intellect dont improve when you change your Ford-enginge in a Ferrari-one. If someone has seen patients suffering from Schizophrenia or other mentally disorders, he has to confess thats not more than a stupid Farce what you do. I feel sorry for you.
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Flex
post Jul 26, 2012, 05:16 PM
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Every experiment needs its subject. In all honesty, I rarely step outside the bounds of the extremely safe and natural. It was not nootropics which caused my episode, just genetics and the right set of life stressors.
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Phi
post Jul 28, 2012, 02:02 AM
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QUOTE(Flex @ Jul 26, 2012, 06:16 PM) *

Every experiment needs its subject. In all honesty, I rarely step outside the bounds of the extremely safe and natural. It was not nootropics which caused my episode, just genetics and the right set of life stressors.


ah, ur back...welcome. I was pretty sure it wouldn't be permanent or long
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