Racetams While You Sleep? Options

[Christsean]

I have Piracetam, Aniracetam, Oxiracetam, and Pramiracetam powders. I have been experimenting with them in various combinations. I am currently taking 500mg Oxiracetam in the morning then 800mg Piracetam twice daily after that about 5 hours apart. Not much noticeable difference in the effects of the Oxiracetam and the Piracetam in my opinion. I take the 750mg of Aniracetam and 300mg Pramiracetam before I go to bed. I was unable to juggle the Aniracetam and Pramiracetam during the day; it made me very sleepy. I wake up with favorable mental characteristics.

My question is, does anyone think that I am receiving any overall benefits from taking the Pramiracetam and Aniracetam at night while I sleep?

[Flex]

The brain is a funny little creature. I think there is a lot of over simplification on the internet, especially in regards to cognitive enhancement. Proper timing of neurotransmitter release, quantity, and duration are all essential; so too is type of neurotransmitter release. It is my personal opinion that one should allow for a natural balance during sleep to allow the body to regulate and do its own thing. I would have a nice lean protein snack before bed (maybe some edamame) some omega 3s and a good multi to ensure proper enzyme function. This should ensure your body has everything it needs to produce the right amount of neurotransmitter, as well as other vital substances.

I have not seen any studies, but I was recently speaking with a professor of mine about novel doping techniques, namely use of acetylcholinesterase inhibitors. While not commonly utilized, you may see performance enhancers (of the athletic variety) in the near future acting on acetylcholine due to its role in muscle firing. If you are like me, you may get very restless legs at night from messing with too much of this stuff. Chances are, if you consider the cost of supplementing, you are probably paying somewhere in the ballpark of $2 a day, to at best achieve high neurotransmitter concentration. By eating, meditating and exercising, you will obtain optimal neurotransmitter concentration (more is not necessarily better) while simultaneously improving your overall health. I would be willing to bet that by increasing your K/Na and omega3/6 ratio, while increasing calcium intake from vegetable sources, you would observe better results. This could be achieved at little to no cost. The added benefit to this method, is the fact that you will increase your capacity to deal with free radicals, and increase membrane fluidity. Mitochondria play a huge role in neural plasticity. That being said, you have an increased demand for glutathione to prevent lipid peroxidation. Membrane fluidity is likely very important for plasticity as well, and with more fluid membranes (more omega 3) you are also more susceptible to oxidative damage.

http://www.ncbi.nlm.nih.gov/pubmed/16788073

http://www.sciencedirect.com/science?_ob=A...39&searchtype=a

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120259/