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> What do you guys know about L-Phenylalaline?
XR500Final
post May 21, 2009, 07:28 PM
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I picked some up for boosting purposes to increase noepinephrine - however it seems to have a cognitive boosting function mentioned in its literature...

I am not sure about it as it is also makes up 50% of Aspartame which is a known excitotoxin..

Your guys thoughts on it?
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GodConsciousness
post May 22, 2009, 03:29 AM
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Phenylalanine is an essential amino acid and precursor to Phenylethylamine (PEA). Phenylalanine also increases the release of norepinephrine and dopamine. It appears that Phenylalanine can also help with learning and memory.

I am just now releasing a new product with Phenylalanine in it called "Neurotine". I have been taking a close look at protein synthesis in the brain and the role of various amino acids and Neurotine is an outgrowth of those efforts. Several key amino acids have a significant impact on neurotransmitter production and regulation, immune system response, and protein biosynthesis to help repair and build neurons.
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LifeMirage
post May 22, 2009, 01:09 PM
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QUOTE(XR500Final @ May 21, 2009, 10:28 PM) *
I picked some up for boosting purposes to increase noepinephrine - however it seems to have a cognitive boosting function mentioned in its literature...

I am not sure about it as it is also makes up 50% of Aspartame which is a known excitotoxin..

Your guys thoughts on it?


Advertisements aside.

I don't see much benefit of it for cognition purposes more so with mood. What aspect of cognition did you want to effect?
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astroidea
post May 22, 2009, 04:28 PM
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Doesn't dopamine in itself benefit cognitive function, as well as learning and memory? Hence adderall shares much of its effects with phenylalanine.
I've taken L-phenylalanine, Tyrosine, and L-dopa, amphetamine, and methylphenidate.

The former three feels very similar. They do improve mood, makes me feel more alive, but not in a stimulated caffeine/amphetamine way. I find that they help the most when I'm cramming for an exam and I'm pumped up. It really supplies for the building blocks of the dopamine and norepinephrine, that is triggered while pumped up. This actually boosts it so much that it actually feels similar to amphetamine, especially when food is taken to boost serotonin and energy stores.

My next buy is going to be phenylalanine after I finish my L-dopa, it's so much cheaper too.



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XR500Final
post May 22, 2009, 07:02 PM
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Actually I am interested in a combination of L-Arginine Pyroglutamate (which crosses the DMSO barrier) in combination with L-Phenylaliline (which converts to L-Tyrosine)

Apparently there is a study that L-Arginine with Tyrosine will greatly increase releases of HGH and speed healing and recovery..

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XR500Final
post May 22, 2009, 07:06 PM
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This is based on research into increasing HGH release an interesting document found here :

http://www.futurescience.com/hgh.html

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GodConsciousness
post May 23, 2009, 05:19 AM
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HGH, NGF, and BDNF all appear to be modulated in part by amino acids and critical to the neurochemistry of the mind.
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GoodFellas
post May 25, 2009, 11:20 AM
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Should I use this for my exam? I have a bottle of 750mg's L-Phenylalaline at home. I've heard that it might be dangerous, but I don't know.
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LifeMirage
post May 25, 2009, 11:02 PM
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QUOTE(astroidea @ May 22, 2009, 07:28 PM) *
Doesn't dopamine in itself benefit cognitive function, as well as learning and memory? Hence adderall shares much of its effects with phenylalanine.
I've taken L-phenylalanine, Tyrosine, and L-dopa, amphetamine, and methylphenidate.

The former three feels very similar. They do improve mood, makes me feel more alive, but not in a stimulated caffeine/amphetamine way. I find that they help the most when I'm cramming for an exam and I'm pumped up. It really supplies for the building blocks of the dopamine and norepinephrine, that is triggered while pumped up. This actually boosts it so much that it actually feels similar to amphetamine, especially when food is taken to boost serotonin and energy stores.

My next buy is going to be phenylalanine after I finish my L-dopa, it's so much cheaper too.


Dopamine does play a role in cognition (more so with focus and motivation than memory) and especially mood but L-Phenylalanine is not a potent precursor to Dopamine, L-DOPA or L-tyrosine would be more direct and effective routes. You may be feeling the effects of PEA from L-Phenylalanine to a degree which amphetamines also increase. Although constant use of L-phenylalanine over time should significantly raise dopamine levels.

QUOTE(GoodFellas @ May 25, 2009, 02:20 PM) *
Should I use this for my exam? I have a bottle of 750mg's L-Phenylalaline at home. I've heard that it might be dangerous, but I don't know.


If you have a metabolic disorder it would be dangerous, however you would know by now if you had it. While it's not my top suggestion for such effects it may be of some benefit.
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XR500Final
post May 26, 2009, 05:53 PM
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I am still concerned about the safety of this product, as there are tons of horror stories related to Aspartame, and it is 50% Phenylalaline...

Is it the aspartic acid, the methonal, or the Phenylalaline that makes it an excito-toxin?
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GodConsciousness
post May 27, 2009, 05:59 AM
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QUOTE(XR500Final @ May 26, 2009, 09:53 PM) *

I am still concerned about the safety of this product, as there are tons of horror stories related to Aspartame, and it is 50% Phenylalaline...

Is it the aspartic acid, the methonal, or the Phenylalaline that makes it an excito-toxin?


Phenylalanine is found in breast milk and considered quite safe. Aspartame, as you mention, contains aspartic acid and methanol. The aspartic acid can cause issues especially in those with various neurodegenerative conditions. Aspartic acid can be an excititory amino acid in a negative way (this is also why people with neurodegerative conditions such as Alzheimer's and Parkinson's Disease should avoid excessive levels of glutamate). And presumably the methanol in aspartame is not helping matters.
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LifeMirage
post May 27, 2009, 03:25 PM
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QUOTE(XR500Final @ May 26, 2009, 08:53 PM) *
I am still concerned about the safety of this product, as there are tons of horror stories related to Aspartame, and it is 50% Phenylalaline...

Is it the aspartic acid, the methonal, or the Phenylalaline that makes it an excito-toxin?


I would suggest focusing your research efforts on L-phenylalanine rather than a synthetic compound that happens to contain it.

Horror stories are not scientifically based.
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sunshinefrost
post Jun 08, 2009, 01:57 PM
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hey
the horror storries probably come from people with phenylkenoturia... read on this condition. people who have this will be victims of excitotoxins from the aspartame.... that's what i understood.

pea really works... i used it without knowing because i took pay attention from smart nutrition.... i use to take get smart and i never had the same feeling... pay attention is much stronger and the biggest difference is the phenyl stuff.

it works but i found out... with 30 hours of research on the web that it's almost like amphetamines. For me amphetamines are the BAD NEWS. so you see ? of course the stuff works.. there is speed in it !!!!

i know that i will be critisized for not putting any reszearch links and by not proving my point. but i tried it and i felt superhuman on this.... it felt like a drug. i scored 3 goals in my hockey game that night and i was very very very calm... i was like in alpha mode or something.

i personaly don't recommend it even if it's a mild drug...

if your goal is to be 200% productive for only 1 day ... like a REALLY important test then you can do it, you won't feel the harm if you use it once.

i don't think it should be advertized as a nootropic if it doesn't protect/improve your neurons
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sunshinefrost
post Jun 17, 2009, 11:25 AM
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what's the difference between PEA and phenylalanine ? one is converted into the other ? The PAY ATTENTION formula (smartnutrition) felt like a drug... too bad, i was really "in the zone" when i tried it. what i want to know is if i teke phenylalanine; will i get the pea (amphetamine) feeling ?

for some reason, on their website(smart-nutrition.net/brain. 8tml): Phenylethylamine is blacked out.... you can't click on the product to see reviews or details about the stuff. wierd !
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GodConsciousness
post Jun 17, 2009, 11:33 AM
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phenylalanine is converted to phenylethylamine (PEA)
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sunshinefrost
post Jun 17, 2009, 12:03 PM
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thanks.

am i right when i say that pea feels like amphetamine but in a smoother kind of way ?
Isn't pea dangerous ?
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GodConsciousness
post Jun 20, 2009, 04:16 AM
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amphetamine is a phenylethylamine- α-methylphenethylamine
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Phi
post Jun 20, 2009, 04:33 AM
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Pea can be dangerous yes
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sunshinefrost
post Jun 23, 2009, 01:40 PM
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thanks for all the info.

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LifeMirage
post Jul 03, 2009, 03:23 PM
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QUOTE(sunshinefrost @ Jun 08, 2009, 04:57 PM) *
hey
the horror storries probably come from people with phenylkenoturia... read on this condition. people who have this will be victims of excitotoxins from the aspartame.... that's what i understood.

pea really works... i used it without knowing because i took pay attention from smart nutrition.... i use to take get smart and i never had the same feeling... pay attention is much stronger and the biggest difference is the phenyl stuff.

it works but i found out... with 30 hours of research on the web that it's almost like amphetamines. For me amphetamines are the BAD NEWS. so you see ? of course the stuff works.. there is speed in it !!!!

i know that i will be critisized for not putting any reszearch links and by not proving my point. but i tried it and i felt superhuman on this.... it felt like a drug. i scored 3 goals in my hockey game that night and i was very very very calm... i was like in alpha mode or something.

i personaly don't recommend it even if it's a mild drug...

if your goal is to be 200% productive for only 1 day ... like a REALLY important test then you can do it, you won't feel the harm if you use it once.

i don't think it should be advertized as a nootropic if it doesn't protect/improve your neurons


Amphetamine while chemically related to phenylethylamine they have very different effects.
Phenylethylamine is an important brain chemical needed for proper brain functioning and deficiencies are common in ADHD and depression to name a few conditions.
With most compounds the dose will yield the result and it would appear you may have used more than your receptors would process.


QUOTE(sunshinefrost @ Jun 17, 2009, 02:25 PM) *
what's the difference between PEA and phenylalanine ? one is converted into the other ? The PAY ATTENTION formula (smartnutrition) felt like a drug... too bad, i was really "in the zone" when i tried it. what i want to know is if i teke phenylalanine; will i get the pea (amphetamine) feeling ?

for some reason, on their website(smart-nutrition.net/brain. 8tml): Phenylethylamine is blacked out.... you can't click on the product to see reviews or details about the stuff. wierd !


L-phenylalanine is a direct precursor to phenyethylamine. Pyridoxine is used by decarboxylase to remove the carboxy group from L-phenylalanine to release the phenylethylamine molecule.


QUOTE(sunshinefrost @ Jun 17, 2009, 03:03 PM) *
thanks.

am i right when i say that pea feels like amphetamine but in a smoother kind of way ?
Isn't pea dangerous ?


If you're looking for an amphetamine effect I would not suggest using phenylethylamine. It can certainly produce negative side effects when abused or taken by those on various medications or health conditions.
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nito
post Jul 04, 2009, 11:27 PM
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Lifemirage can you take L-tyrosine while you're taking st johns wort and bacopa?
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LifeMirage
post Jul 05, 2009, 02:44 AM
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QUOTE(nito @ Jul 05, 2009, 02:27 AM) *
Lifemirage can you take L-tyrosine while you're taking st johns wort and bacopa?


Provided you are on no other medications I do not see any direct interaction, although it may bolster some of the effects of St John's wort.
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nito
post Jul 05, 2009, 05:56 PM
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QUOTE(LifeMirage @ Jul 05, 2009, 02:44 AM) *

QUOTE(nito @ Jul 05, 2009, 02:27 AM) *
Lifemirage can you take L-tyrosine while you're taking st johns wort and bacopa?


Provided you are on no other medications I do not see any direct interaction, although it may bolster some of the effects of St John's wort.



Hopefully it won't bolster any negative side effects but only support the positive mood enhancement.
I also hear tyrosine can play part in skin pigmentation, i hope it doesen't darken me or something.
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LifeMirage
post Jul 06, 2009, 10:12 PM
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QUOTE(nito @ Jul 05, 2009, 08:56 PM) *
QUOTE(LifeMirage @ Jul 05, 2009, 02:44 AM) *

QUOTE(nito @ Jul 05, 2009, 02:27 AM) *
Lifemirage can you take L-tyrosine while you're taking st johns wort and bacopa?


Provided you are on no other medications I do not see any direct interaction, although it may bolster some of the effects of St John's wort.



Hopefully it won't bolster any negative side effects but only support the positive mood enhancement.
I also hear tyrosine can play part in skin pigmentation, i hope it doesen't darken me or something.


L-tryosine is a precursor for melanin which can effect your skin color.

If you avoid tanning and use sunscreen it should help prevent discoloration.
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nito
post Jul 07, 2009, 12:10 PM
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good lord! I cut open a st johns wort pill and swallowed it with water. Felt nauseated all morning and sick lol.
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mustang
post Mar 23, 2012, 01:46 PM
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QUOTE(XR500Final @ May 21, 2009, 07:28 PM) *

I picked some up for boosting purposes to increase noepinephrine - however it seems to have a cognitive boosting function mentioned in its literature...

I am not sure about it as it is also makes up 50% of Aspartame which is a known excitotoxin..

Your guys thoughts on it?



Aspar... also has wood alcohol which makes a formelgahyde that the body does not metabolize. If you are craving a drink after this it is because the body "thinks" the new alcolohs formelgahyde will help rid itself of the buildup. But it does not.

Also it is a bad excitotoxin. Which causes alot of problems in itself.
Many people also get allergic reactions to the hydrolyzed form of aspartate protein in it, and enhances other more benign allergies. Red swollen eye lids, itching burning stinging type of rashes on the neck. etc..

And there is the L-Phenylalaline in it. Well some people can not tolerate that either. So I would not use that product even if it was free.
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