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> Can we please have a treatment for depression yet?
Tone
post Apr 03, 2009, 08:54 PM
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just asking, can we?

"No you may not we shall ban everything, and you will only get what doctors and the FDA says youll get for depression, i dont give a frak that it doesnt work, you must suffer in torture, suffer and commit suicide, i dont care, you cannot try or have anything you want because i say so, no matter how desperate and tortured you are"

The above sentence quote reflects the government, FDA, DEA, mainstream psychiatry and most the population, even if they try and claim "no its not that is your distorted opinion" it doesnt matter if they know it or not, the above quote is the objective black and white truth and depression is such torture-agony-torture-suffering of torture, that they should be allowed to try and have anything they want and be able to try to get relief from super-destroyed life of torture.

If i could talk to congress, the FDA, the beurocrats, a panel of some psychiatry association, i absolutely guarantee you , i could crush them in any debate, easily, and advocate the real truth to those frakin' robots who dont experience torture. This isnt about two sides of an argument each having points...this is far beyond that and about truth and ethics. these **** suckers never suffer and dont know what its like and yet dictate to depressives that they cant have and try anything they want for a totally and utterly destroyed life?
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rhymer
post Apr 04, 2009, 01:58 PM
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Hi Tone,
Can you not get access to antidepressants?
How many have you tried?
Are they for you or a friend?
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Tone
post Apr 04, 2009, 06:51 PM
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QUOTE(rhymer @ Apr 04, 2009, 04:58 PM) *

Hi Tone,
Can you not get access to antidepressants?
How many have you tried?
Are they for you or a friend?



I dont know, about 40 of various classes
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Hey Hey
post Apr 05, 2009, 03:50 PM
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Is it actually depression? There are so many varieties. Bipolar is also very common. Sometimes there are multiple conditions. Dependent upon the diagnosis, the drug regime will be different. It can be varied and protracted for some. Have you had ECT? Just to pin this down, have you been diagnosed with clinical depression? Is there also anxiety, delusion, mania or any other symptom?
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Tone
post Apr 06, 2009, 04:37 PM
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QUOTE(Hey Hey @ Apr 05, 2009, 06:50 PM) *

Is it actually depression? There are so many varieties. Bipolar is also very common. Sometimes there are multiple conditions. Dependent upon the diagnosis, the drug regime will be different. It can be varied and protracted for some. Have you had ECT? Just to pin this down, have you been diagnosed with clinical depression? Is there also anxiety, delusion, mania or any other symptom?



Hey Hey, i never, ever, ever feel well. I NEVER have bursts of energy where i get things done. In other words, i never have mania stages. the only way that can happen is with a drug and it would be very mild and weak compared to other people's natural mania. even with a drug i still wont clean or laugh or do anything like others and their strong mania.

regardless of my diagnosis, i already tried everything, and none of those drugs feel good, no matter if they are a mood stabilizer or an SSRI. they all feel bad and dont help, or make things worse by inducing suffering stronger.

I cant try ECT because other major depressives say it doesnt work and only causes memory loss and damage they cant reverse. I even talked to one personally at a place where i used to see another doctor. Im 100% positive that if i did ECT it would cause irreversible damage with no benefit, bringing me even more desperate for suicide.

Drugs can be reversed almost always, by stopping them, ECT cannot, if ECT goes wrong, the victim can only commit suicide, there is no reversing of its side effects.

I feel Anhedonic and dysphoria all of the time, i have no other state i shift to, ever, and ive been this way since i was born.
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catseye
post May 02, 2009, 02:24 PM
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QUOTE(Tone @ Apr 06, 2009, 04:37 PM) *

QUOTE(Hey Hey @ Apr 05, 2009, 06:50 PM) *

Is it actually depression? There are so many varieties. Bipolar is also very common. Sometimes there are multiple conditions. Dependent upon the diagnosis, the drug regime will be different. It can be varied and protracted for some. Have you had ECT? Just to pin this down, have you been diagnosed with clinical depression? Is there also anxiety, delusion, mania or any other symptom?



Hey Hey, i never, ever, ever feel well. I NEVER have bursts of energy where i get things done. In other words, i never have mania stages. the only way that can happen is with a drug and it would be very mild and weak compared to other people's natural mania. even with a drug i still wont clean or laugh or do anything like others and their strong mania.

regardless of my diagnosis, i already tried everything, and none of those drugs feel good, no matter if they are a mood stabilizer or an SSRI. they all feel bad and dont help, or make things worse by inducing suffering stronger.

I cant try ECT because other major depressives say it doesnt work and only causes memory loss and damage they cant reverse. I even talked to one personally at a place where i used to see another doctor. Im 100% positive that if i did ECT it would cause irreversible damage with no benefit, bringing me even more desperate for suicide.

Drugs can be reversed almost always, by stopping them, ECT cannot, if ECT goes wrong, the victim can only commit suicide, there is no reversing of its side effects.

I feel Anhedonic and dysphoria all of the time, i have no other state i shift to, ever, and ive been this way since i was born.



Just some quick questions.
Have you tried anything outside of drugs that will alter your state of living? have you tried to attempt a personal regime (without giving up) that focuses on planning your day around activities that retrain your thought process ? it is difficult to understand that you were "born" like this. To say it has been this way since age 10 or so, yes, but before this we, as human beings, are in a stage of reception, no one is born depressed. Depression is a learned condition brought on by hardships that lay deep within our emotional construct and form a constant response - action cycle. The only real way to undo this cycle is to create a different cycle that a person must work very hard at to redevelop and eventually becomes natural.
It requires a redirection of "thinking" instead of focusing on the typical outcome of any situation, stop the expectation. Let the mind anticipate...nothing, but let a moment be for itself, and to be discovered.
It requires a redirection of feeling. Instead of letting one emotion run through it's course, stop. Engage in a method that works for you to "choose" your emotion. You control what you feel, not your feelings controlling you.
Start a physical activity that takes you "outside" YOUR world. Get involved in volunteering, teaching or service. Or start walking everyday but make it something that takes you to new places to give an outside stimulus. Map out different areas of the city or county that you haven't been. Give yourself a destination and a goal. Let yourself be satisfied with a start and finish in this accomplishment.
Drugs or prescriptions are to help start this, but they can not fix that which only you can change.

And Happy Birthday Tone !
This life is worth living.
This day is worth Celebrating.
You are.


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correlli
post May 03, 2009, 11:30 PM
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I find new clothes and shoes makes me feel wonderful.
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mk-ultra
post May 04, 2009, 09:37 AM
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QUOTE(correlli @ May 04, 2009, 12:30 AM) *

I find new clothes and shoes makes me feel wonderful.


Tone doesn't strike me as having the type of personality who can head to the mall and buy his way out of this.

Buying things is too ephemeral of a fix anyway. Unless you're a teenager, or a very superficial person. (or the perfect consumer some call it)
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correlli
post May 04, 2009, 10:13 PM
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QUOTE(mk-ultra @ May 04, 2009, 09:37 AM) *

QUOTE(correlli @ May 04, 2009, 12:30 AM) *

I find new clothes and shoes makes me feel wonderful.


Tone doesn't strike me as having the type of personality who can head to the mall and buy his way out of this.

Buying things is too ephemeral of a fix anyway. Unless you're a teenager, or a very superficial person. (or the perfect consumer some call it)



Tone should try it. You don't need alot of money to look good.
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Hey Hey
post May 15, 2009, 05:30 PM
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Potential New Drug Target for Depression Identified

Wednesday, April 29, 2009

Disrupting an acid-sensitive protein in the brain produces antidepressant effects

An acid-sensitive protein in the brain may represent a new target for the treatment of depression, according to animal research in the April 29 issue of The Journal of Neuroscience. The study shows that disrupting acid-sensitive ion channel-1a (ASIC1a) produces antidepressant-like effects in mice. The findings may one day benefit people who do not respond to traditional antidepressants or who cannot tolerate their side effects.

"Depression is one of the most devastating and difficult-to-treat disorders known to man," said John F. Cryan, PhD, at University College Cork in Ireland, who was not affiliated with the study. "Despite much research, all antidepressant medications that are currently prescribed work in much the same way and are of limited efficacy in more than a third of all patients. The development of antidepressants that act on other molecular targets in the brain would be a major breakthrough," Cryan said.

Although animal models cannot reproduce all of the symptoms of human depression, several behavioral tests in rodents are sensitive to antidepressant treatment, suggesting that they address important aspects of the disease. For example, chronically stressed mice lose their normal preference for sugary drinks, and mice repeatedly placed in a pool of water tend to give up and float rather than swim in the hopes of escaping. These mouse behaviors are thought to reflect loss of interest in pleasurable activities and hopelessness or despair. But traditional antidepressants are able to restore the mouse preference for sweet treats and reduce the amount of time that they float rather than swim.

The researchers, led by Matthew Coryell, PhD and senior researcher John Wemmie, MD, PhD, at the University of Iowa, found that mice lacking the ASIC1a gene and normal mice treated with drugs that inhibit ASIC1a showed reduced depression-like behaviors. These mice showed increased sweet taste preference and reduced immobility, consistent with antidepressant treatment.

Mice lacking the ASIC1a gene also failed to show a known biomarker for depression. Chronic stress normally decreases the amount of the BDNF gene in the brain, but mice lacking ASIC1a failed to show this change.

The researchers found that ASIC1a-based treatment works through a different biological pathway than traditional antidepressants, suggesting that it may benefit people who do not respond to traditional therapies.

ASIC1a is located in brain structures associated with mood, including the amygdala, which is critical for so-called negative emotions such as anger, anxiety, and fear. The researchers previously showed reduced amygdala activity in animals that lacked the ASIC1a gene. In the current study, they reversed the antidepressant effect of ASIC1a gene deletion by turning the ASIC1a gene back on only in the amygdala. These findings support the idea that depression could be caused, at least in part, by hyperactivity of the amygdala.

"ASIC1a inhibitors may combat depression by reducing amygdala activity. Because of the importance of the amygdala in negative emotions and fear, we speculate that ASIC1a inhibition increases the brain's resistance to the negative effects of stress, perhaps reducing the likelihood of developing depression," said study author Wemmie.

The research was supported by the National Institute of Mental Health, the National Alliance for Research on Schizophrenia and Depression, and the Department of Veteran Affairs.

The Journal of Neuroscience is published by the Society for Neuroscience, an organization of more than 38,000 basic scientists and clinicians who study the brain and nervous system. Wemmie can be reached at john-wemmie@uiowa.edu.
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rockmartinn24
post Aug 19, 2010, 06:07 AM
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Depression is a recoverable disease. Depression is a listed mental disorder which includes altered mood. Never fear from depression disease. Some tips for come out from depression are listed below.

1. Consult the right medical doctor

2. Take proper Medicine

3. Listen music

4. Chat and play with friends

5. Take sunlight

6. Play games

7. Family Support
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GodConsciousness
post Aug 19, 2010, 06:21 AM
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QUOTE(rockmartinn24 @ Aug 19, 2010, 10:07 AM) *

Depression is a recoverable disease. Depression is a listed mental disorder which includes altered mood. Never fear from depression disease. Some tips for come out from depression are listed below.

1. Consult the right medical doctor

2. Take proper Medicine

3. Listen music

4. Chat and play with friends

5. Take sunlight

6. Play games

7. Family Support


Sunlight, family and good friends can do wonders.
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jupiterpitter
post Aug 25, 2010, 07:28 PM
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No there is no medical treatment for depression . Depression is the thing that happen to every one in there life you have to do one thing that make your self busy and make your mind relax do meditation, exercise, music, dance, read books this all thing help you to solve the problem of depression.
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Hey Hey
post Aug 25, 2010, 09:27 PM
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QUOTE(jupiterpitter @ Aug 26, 2010, 04:28 AM) *

No there is no medical treatment for depression . Depression is the thing that happen to every one in there life you have to do one thing that make your self busy and make your mind relax do meditation, exercise, music, dance, read books this all thing help you to solve the problem of depression.
I think we are talking about clinical depression in this topic. Thus such flippant remarks are worthless.
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