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> Survey of antidepressant rankings, ..for efficacy and tolerance
rhymer
post Jan 30, 2009, 12:16 PM
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Antidepressants compared

Jan. 29, 2009

To rate the 12 antidepressants studied, researchers used two separate measures. The first was efficacy -- or how likely patients were to experience the desired effects of the drug. The second was acceptability -- the likelihood that a patient would continue using a drug for the duration of the study (it is generally assumed that a high ratio of patients dropping out indicates the presence of undesirable side effects for a drug).

A study set out to rank the top 12 antidepressants in terms of efficacy and likely side effects.
(Getty/ABC News)

Efficacy:

1) Mirtazapine (Remeron)
2) Escitalopram (Lexapro)
3) Venlafaxine (Effexor)
4) Sertraline (Zoloft)
5) Citalopram (Celexa)
6) Buproprion (Wellbutrin)
7) Paroxetine (Paxil)
8) Milnacipran (Savella)
9) Fluoxetine (Prozac)
10) Duloxetine (Cymbalta)
11) Fluvoxamine (Luvox)
12) Reboxetine (Vestra)

Acceptability:

1) Sertraline (Zoloft)
2) Escitalopram (Lexapro)
3) Buproprion (Wellbutrin)
4) Citalopram (Celexa)
5) Fluoxetine (Prozac)
6) Milnacipran (Savella)
7) Mirtazapine (Remeron)
8) Venlafaxine (Effexor)
9) Paroxetine (Paxil)
10) Duloxetine (Cymbalta)
11) Fluvoxamine (Luvox)
12) Reboxetine (Vestra)

Source: Cipriani et al, "Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis." Lancet (2009).

http://abcnews.go.com/Health/MindMoodNews/...=6752317&page=1
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Hey Hey
post Jan 30, 2009, 12:22 PM
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The modern way to treat mental (and other) illness.

http://www.curidium.com/
http://www.theragenetics.com/

I have a tangentially vested interest so I won't comment any more. I just wanted to flag the approach.
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rhymer
post Jan 30, 2009, 12:49 PM
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We really would benefit from successes these companies may achieve!
Medication in mental health really is a trial and error approach presently. And, unfortunately, many give up too soon (cure not found) because of unwanted side-effects ie incompatibilities between drug applied and human body chemistry.
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Hey Hey
post Jan 30, 2009, 01:40 PM
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QUOTE(rhymer @ Jan 30, 2009, 08:49 PM) *
And, unfortunately, many give up too soon (cure not found) because of unwanted side-effects ie incompatibilities between drug applied and human body chemistry.
Important statement.
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