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> How much does a 0.5mm slice of brain matter?
post Jul 13, 2008, 03:24 AM
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It helps illustrate my question to give the medical background, although I'm interested in the scientific aspect.

N has a 10mm diameter spherical brain tumor in his left motor cortex just below the surface. It causes paralysis of his fingers, currently temporarily alleviated through use of an anti-inflammatory steroid.

He is due to have radio surgery.

We had expected the medical team to target a 9mm concentric sphere so as to leave a .5 mm safety margin, thereby avoiding damage to adjacant brain tissue.
The team see it differently, and intend to target an 11mm sphere so as to catch all the cancer and eliminate the possibility of regrowth.

How significant is the loss of 0.5mm of brain tissue at the periphery of the tumor,in the motor cortex, likely to be? Permanant loss of function likely?

Thanks Tony

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post Jul 13, 2008, 09:36 AM
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.5 mm of cortex is not much, a mere fraction of the 250,000 mm2 total cortical surface area, and I would not expect that its loss would result in significant motor deficits.
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post Jul 13, 2008, 03:38 PM
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There is an illuminating article on wiki p....

All the best for your associate!!
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