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> L-Huperzine A, Acetylcholinesterase inhibitor
cerebral
post Mar 05, 2006, 09:22 PM
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Anyone have experience with Huperzine A?

According to uniquenutrition.net:
L-Huperzine A is a natural plant alkaloid (extracted from Huperzia serrata), which quickly and potently boosts memory, learning, and concentration. Used worldwide for decades in adults and high school students. Is considered the most potent short term memory enhancer available.

What's the best place to buy this?



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semi-retarded-individual
post Feb 25, 2012, 10:54 AM
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I'm somewhat familiar with LifeMirage's position on Hup A because I've been researching this substance extensively... however most of his posts supporting its use are from 2008. LM, has your view on Hup A changed at all? I know you say you've prescribed it to over 5,000 patients over the duration of your career as a MD. Do you still regard it as safe despite the warnings?

A user on Longecity put together a comprehensive post with sources concerning the dangers of Huperzine A use. I would link to it but because my post count is so low, I can't.

Search Longecity for the thread titled "AChEIs (Acetylcholinesterase Inhibitors)/Huperzine A Dangers".

LM... are you still advocating its usage now the same way you did in 2008? Any new safety concerns?
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Jakare
post Feb 25, 2012, 03:02 PM
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QUOTE(semi-retarded-individual @ Feb 25, 2012, 07:54 PM) *

I'm somewhat familiar with LifeMirage's position on Hup A because I've been researching this substance extensively... however most of his posts supporting its use are from 2008. LM, has your view on Hup A changed at all? I know you say you've prescribed it to over 5,000 patients over the duration of your career as a MD. Do you still regard it as safe despite the warnings?

A user on Longecity put together a comprehensive post with sources concerning the dangers of Huperzine A use. I would link to it but because my post count is so low, I can't.

Search Longecity for the thread titled "AChEIs (Acetylcholinesterase Inhibitors)/Huperzine A Dangers".

LM... are you still advocating its usage now the same way you did in 2008? Any new safety concerns?

Itīs been a while since last time LM posted here so I donīt think you are getting an answer, at least a public one.
I am a usual lurker of Longecity and I linked that thread here in BM once at least. AChEIs are some of the most potent nootropics I have tried and because of that I pay them respect. For me they are a tool for special occasions and not a daily or chronic supp.
It would be really interesting to know LM response to your question but for me the dangers are there and are not meant to be ignored.
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semi-retarded-individual
post Feb 25, 2012, 03:56 PM
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QUOTE(Jakare @ Feb 25, 2012, 03:02 PM) *

QUOTE(semi-retarded-individual @ Feb 25, 2012, 07:54 PM) *

I'm somewhat familiar with LifeMirage's position on Hup A because I've been researching this substance extensively... however most of his posts supporting its use are from 2008. LM, has your view on Hup A changed at all? I know you say you've prescribed it to over 5,000 patients over the duration of your career as a MD. Do you still regard it as safe despite the warnings?

A user on Longecity put together a comprehensive post with sources concerning the dangers of Huperzine A use. I would link to it but because my post count is so low, I can't.

Search Longecity for the thread titled "AChEIs (Acetylcholinesterase Inhibitors)/Huperzine A Dangers".

LM... are you still advocating its usage now the same way you did in 2008? Any new safety concerns?

Itīs been a while since last time LM posted here so I donīt think you are getting an answer, at least a public one.
I am a usual lurker of Longecity and I linked that thread here in BM once at least. AChEIs are some of the most potent nootropics I have tried and because of that I pay them respect. For me they are a tool for special occasions and not a daily or chronic supp.
It would be really interesting to know LM response to your question but for me the dangers are there and are not meant to be ignored.


I appreciate your response. I think I will proceed with caution but I do intend to experiment with it. I suppose any detrimental effects won't be immediately perceptible. Instead of lurking at Longecity, you should register and contribute!

I didn't realize LM stopped posting around here. I thought he was a moderator? Isn't he duty-bound to respond to me? happy.gif

Is Galantamine any safer in this respect or does it pose the same threats being that it is also an AChEI?
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Jakare
post Feb 26, 2012, 03:35 AM
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QUOTE
I appreciate your response. I think I will proceed with caution but I do intend to experiment with it. I suppose any detrimental effects won't be immediately perceptible.

In such case maybe you would like to know green tea potentiate Hupezine effects:
http://www.ncbi.nlm.nih.gov/pubmed/19622237
And Alcar an hupezine compete to pass the BBB (Ok in rats) so maybe better not together:
http://www.ncbi.nlm.nih.gov/pubmed/22359054

QUOTE
Instead of lurking at Longecity, you should register and contribute!

Well to be honest I do intend to do so some day this year.

QUOTE

I didn't realize LM stopped posting around here. I thought he was a moderator? Isn't he duty-bound to respond to me? happy.gif

LM did some extensive work here but he couldnīt scape the doubts about him or simply got bored and stopped posting. In these years his work has become dusty and outdated but is anyway a good reading for those who want to learn about nootropics and supps.


QUOTE
Is Galantamine any safer in this respect or does it pose the same threats being that it is also an AChEI?

Donīt know, it has been prove to be safe in AD patients for 3 years:
http://www.ncbi.nlm.nih.gov/pubmed/22003296
Doses:
http://www.ncbi.nlm.nih.gov/pubmed/19358618
but I doubt the data can be extrapolated to young healthy individuals and doses should be a lot smaller. Young healthy subjects sure want to live in good conditions for more than a decade, donīt we? Hey, but the data looks really good for AD patients.
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Posts in this topic
cerebral   L-Huperzine A   Mar 05, 2006, 09:22 PM
cerebral   Here's more info I found: Huperzine Introduct...   Mar 05, 2006, 09:28 PM
LifeMirage   [size=2]I've used and given Huperzine A to man...   Mar 05, 2006, 09:49 PM
Tone   Im not sure why but any nootropic ive tried has in...   Mar 06, 2006, 05:23 PM
cerebral   how much daily dosage is recommended for huperzine...   Mar 11, 2006, 01:41 PM
LifeMirage   Depends on what other ACh compounds you are taking...   Mar 11, 2006, 01:58 PM
cerebral   I take wheat germ, which supposedly has high phosp...   Mar 11, 2006, 02:01 PM
LifeMirage   PC is a very slow acting source of choline for A...   Mar 11, 2006, 02:07 PM
cerebral   is ALC just always pricey? I would take more but ...   Mar 11, 2006, 02:10 PM
LifeMirage   Well there are several sources out there I take a ...   Mar 11, 2006, 02:14 PM
cerebral   I ended up getting some formula containing huperzi...   Mar 11, 2006, 04:04 PM
LifeMirage   If too much is taken nausea, headaches, dizzines...   Mar 11, 2006, 04:58 PM
Pedro   i don't know if it's ok to say - i buy my ...   Apr 02, 2006, 09:44 PM
LifeMirage   Its a low dose but if it works stick with it.   Apr 02, 2006, 10:01 PM
discintilldeath   Hey Lifemirage... if i play disc golf, which is a ...   Jul 08, 2007, 06:35 PM
LifeMirage   Hey Lifemirage... if i play disc golf, which is a...   Jul 08, 2007, 06:51 PM
Underman   ACHe is there for a reason. Inhibiting ACHe long t...   Mar 05, 2010, 12:16 PM
shady   ACHe is there for a reason. Inhibiting ACHe long ...   Mar 18, 2010, 06:14 PM
thinker67   You wanted to know an inexpensive place to buy hup...   Mar 27, 2010, 01:14 AM
Alexander   ACHe is there for a reason. Inhibiting ACHe long ...   Jan 20, 2012, 06:04 PM
sambocyn   to correct several factual and logical errors... ...   Feb 18, 2012, 09:26 PM
cheekyleopard   For cheap supplements (including huperzine) i reco...   Mar 29, 2010, 12:29 AM
trevdawg   Has anyone heard of Cerebral Success? i found it w...   Jan 31, 2012, 11:27 PM
Jakare   Overall it is just a mix of well known substances ...   Feb 02, 2012, 02:16 PM
semi-retarded-individual   I'm somewhat familiar with LifeMirage's po...   Feb 25, 2012, 10:54 AM
Jakare   I'm somewhat familiar with LifeMirage's p...   Feb 25, 2012, 03:02 PM
semi-retarded-individual   I'm somewhat familiar with LifeMirage's ...   Feb 25, 2012, 03:56 PM
Jakare   In such case maybe you would like to know green ...   Feb 26, 2012, 03:35 AM
k_swift1   Originally got my 200 mcg from Cognitive Nutrition...   Jun 10, 2012, 07:54 AM
Rmorgan   Originally got my 200 mcg from Cognitive Nutritio...   Jul 01, 2012, 08:20 PM
Tone   Dead ends, I tried Memantine. Something has to be ...   Jun 10, 2012, 10:26 AM
KoolK3n   AMPA Antagonist barely exist, Stablon is obscure,...   Jun 10, 2012, 01:38 PM
LeeCrostM.D.   I'm somewhat familiar with LifeMirage's p...   Jul 02, 2012, 05:40 AM
Astralogic   I was going to buy some L-Huperzine-A and begin su...   Jul 08, 2012, 12:40 AM
Flex   Ok I challenged LM before and will challenge again...   Jul 09, 2012, 09:43 PM
xsiv1   Ok I challenged LM before and will challenge agai...   Sep 24, 2013, 07:46 AM


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