BrainMeta.com Forum > Feedback, Announcements & FAQ > Announcements > Legal Challenges issued to Mind-Brain.com; Forced to Change Domain Name by Dec 02Last 10 Posts [ In reverse order ]
| Posted Jun 17, 2005, 10:27 AM | |||
| the page you're interested in can be found here: http://brainmeta.com/abstracts.php?qa=DMPG -Shawn |
|||
| Posted Jun 17, 2005, 02:55 AM | |||
| DMPG Chemoselective nucleophilic attack on N-acyl derivatives of (S)-ethyl 4,4-dimethyl pyroglutamate (DMPG). [link] [reaction: see text] Heteronucleophiles and C-nucleophiles chemoselectively react with N-acyl (S)-ethyl 4,4-dimethyl pyroglutamate (DMPG) affording esters, amides, and ketones in high yield. The intramolecular process allows the stereoselective formation of beta-hydroxy acids likely by formation and ring opening of the corresponding beta-lactones Phospholipid black foam films: dynamic contact angles and gas permeability of DMPC+DMPG black films. [link] The behavior of black foam films from aqueous dispersions of dimyristoylphosphatidyl-choline (DMPC) with addition of the soluble phospholipid dimyristoylphosphatidylglycerol (DMPG) has been studied in dynamic conditions. The dynamic contact angles theta and the gas permeability coefficient K have been measured using the diminishing bubble method. The DMPC vesicle suspension in water is obtained through sonication and DMPG is dissolved in it. Two solutions with different NaCl concentrations (0.1 M and 0.5 M) have been studied. The behavior of the dynamic contact angles is very different for DMPC black films with, and without DMPG, respectively. They follow very different time dependence during spontaneous or forced variations of the bubble size. The gas permeability coefficient is significantly reduced by the DMPG addition. The NaCl concentration also influences this specific behavior. It seems that the electrically charged DMPG anions, which determine a significant electrostatic disjoining pressure, play an important role for this specific behavior. The results are discussed in connection with data regarding the thickness and structure of these black foam films. Films from DMPC+DMPG solutions in ethanol plus water mixed solvent have been studied as well, but no quantitative results could be obtained. DMPG gel-fluid thermal transition monitored by a phospholipid spin labeled at the acyl chain end. [link] Low ionic strength aqueous dispersion of dimyristoyl phosphatidylglycerol (DMPG) presents a rather peculiar gel-fluid thermal transition behavior. The lipid main phase transition occurs over a large temperature interval (ca. 17 degrees C), along which several calorimetric peaks are observed. Using lipids spin labeled at the acyl chain end, a two-peak electron spin resonance (ESR) spectrum is observed along that temperature transition region (named intermediate phase), at three different microwave frequencies: L-, X- and Q-bands. The intermediate phase ESR spectra are analyzed, and shown to be most likely due to spin labels probing two distinct types of lipid organization in the DMPG bilayer. Based on the ESR spectra parameters, a model for the DMPG intermediate phase is proposed, where rather fluid and hydrated domains, possibly high curvature regions, coexist with patches that are more rigid and hydrophobic. New leptin receptor mutations in mice: Lepr(db-rtnd), Lepr(db-dmpg) and Lepr(db-rlpy). [link] Three new spontaneous recessive mouse mutations in the leptin receptor gene (Lepr), Lepr(db-rtnd), Lepr(db-dmpg) and Lepr(db-rlpy), originated in the CBA/J (CBA), B10.D2-H8(  (57N)/Sn (B10) and NU/J strains, respectively. Lepr(db-rtnd) and Lepr(db-dmpg) were maintained on C57BL/6J (B6), resulting in congenic lines of B6.CBA-Lepr(db-rtnd) and B6.B10-Lepr(db-dmpg). Lepr(db-rtnd) was also maintained on CBA post F1 generation of a cross between the B6 and the CBA, generating the congenic line CBA.B6CBA-Lepr(db-rtnd). Lepr(db-rlpy) was maintained as a coisogenic strain. The aims of this study were to determine the molecular bases for these new Lepr mutations and to characterize the new mutant stocks, with respect to obesity and diabetes. Mutations were analyzed by Southern blot analysis, reverse transcriptase-polymerase chain reaction and sequencing. Body weights and plasma glucose and insulin levels were measured, and the histology of the pancreas was carried out. Lepr(db-rtnd) contained one G deletion in exon 4 of Lepr, introducing a frameshift and premature termination. Lepr(db-dmpg) had a deletion in the extracellular domain of LEPR: Lepr(db-rlpy) exhibited a large DNA deletion, leading to a complete lack of LEPR: All three mutations led to morbid obesity and diabetes. It is noteworthy that Lepr(db-rtnd) caused milder hyperglycemia accompanied by higher plasma and pancreatic insulin contents on B6 compared to that on CBA backgrounds. In summary, we discovered three new mutations of Lepr, providing new mouse models for obesity and diabetes. Furthermore, our mutant stocks will be useful in elucidating the effects of the genetic background on the Lepr mutations and in testing the specificity of antibodies to LEPR.If you need more, ask again; good luck. |
|||
| Posted Jun 16, 2005, 11:02 PM | |||
| A page I am deadly interested in is not accessible ! Here is the address: mind-brain.com/abstracts.php?qa=DMPG. Instead, I was being redirected automatically to brainmeta.com This info is realy important for my research on synthetic neuropeptides designed to cure PAIN. What is going on in this world ? |
|||
| Shawn | Posted Feb 06, 2005, 06:19 PM | ||
| Good point, MC. There's little point in focusing any more energy on this negative topic. | |||
| Posted Jan 25, 2005, 08:24 PM | |||
| Is this discussion board not a contradiction of the essence of what BrainMeta is supposed to represent? Why focus any energy on a topic of this nature? |
|||
| Enki | Posted Nov 14, 2004, 07:00 PM | ||
| Exactly! | |||
| Posted Nov 14, 2004, 06:44 PM | |||
| maybe JHU is trying to benefit off of the web popularity that 'mind-brain.com' has enjoyed? I doubt that's their primary motive, but I'd be surprised if it didn't factor into their equation. | |||
| Enki | Posted Nov 14, 2004, 06:11 PM | ||
First of all when you quote others’ words Robert take care of putting frames, otherwise people may mix who wrote what [there is a small link in the right upper corner called quote], develop this culture of communication: respect readers. Though you never care to make rigid references to your writings, as you do not have academic mindset. Second, the site was functioning for several years as far as I understood, and it looks like all were happy in the JHU, I mean there were not any problems. So what a MIRACULOUS change have happened that they persistently want NOW to take the LOGO by 2 December? I think it is interesting question. Interesting Esoteric Question. Third, you personally was using this forum very intensively, so I wonder how you so easily concluded that Shawn “ripped off the name” without any evidence? More probably it looks like that JHU due to some UNKNOWN motivating factors decided just to grab popular LOGO. Looks like that that VERY IDEA probably was input into the BRAINS of some people of the University from outside [or was advised from outside]. I am not quite sure, but that looks like so. If my suspicions are true then it will be VERY interesting to know WHO and WHY did so. Forth, I think that if Shawn needs any support, he must be helped. Certainly it will be very difficuly for him to oppose those demands if he studies in JHU. Actually I think that he is absolutely restricted in activities to protect his LOGO so that is why he transpose the forum LOGO from mind-brain.com to brainmetha.com, and possibly starting from 2 December when one will type mind-brain.com in the explorer address bar he will enjoy JHU site by then. And I am quite sure that Shawn is not be able to say to the site visitors and members that he needs help as his future life and career in some way or another is related with JHU. BUT I think that Intelligent and people having Free Will, possible have to think how to let JHU guys, and especially those who initiated this LOGO shift, to know about those negative feelings which have risen among the site visitors after observation of that particular Administrative injustice, though even if Shawn made peace and subdued to the high will of the University. I mean that ladies and gentlemen have to turn up creativity and sagacity and each invent a curious, interesting, alluring and funny way of how to make that remark. I mean that the guys from JHU MUST be reminded that Each MUST Cultivate His/Her Own Garden and not try to dig holes in other places. I just want to say that Shawn had good intentions opening this site (the site promotes Knowledge, helps to put new bricks on bricks thus constricting the magnificent building of the Civilization) and as is known the good intentions directed at building something always must be protected. That is the truth known from very old times. I wonder that I must remind about that from time to time. Thank you in advance, All the bests, Enki |
|||
| Posted Nov 14, 2004, 02:13 PM | |||
RTB, you've failed to show that Shawn ripped off the name. Even if he was involved with the Krieger Mind-Brain Institute at the time of conception of the domain name 'mind-brain.com' does not constitute convincing proof that he ripped off the name. To say that he did so is just plain irresponsible. You should know better, but I guess no-one can put anything beneath you. |
|||
| Posted Nov 14, 2004, 01:59 PM | |||
| Ignorance is Bliss Shawn created the problem by ripping off the name. If Shawn is of the same opinion, then it is not necessary to mention the name of the Person(s) who creates problems to the site from the University. Anyway I think there will be quite many interesting people who can conduct reliability testing of the firewalls of the university servers. I mean 6000-12000 visitors per day it is a significant number. You know probability, ideas percolation. I mean people from the JHU must weigh and consider what they do before implementing questionable strategies of grabbing others LOGO. It does not matter if JHU got one visitor a year they would have Prior usage of the name. |
|||
| Review the complete topic (launches new window) | |||
| Lo-Fi Version | Time is now: 23rd May 2013 - 03:18 PM |
Copyright © BrainMeta. All rights reserved.
Terms of Use | Last Modified Tue Jan 17 2006 12:39 am